Department of Ophthalmology and Visual Science, Tokyo Medical and Dental University, Tokyo, Japan.
Topcon Corporation, Tokyo, Japan.
Retin Cases Brief Rep. 2023 Sep 1;17(5):542-547. doi: 10.1097/ICB.0000000000001241.
The purpose of this study was to investigate the deep structural abnormalities in the patients with morning glory syndrome by using swept source optical coherence tomography.
The papillary and peripapillary areas of the four eyes (four patients) with morning glory syndrome were examined with a prototype swept source optical coherence tomography system with a center wavelength of 1,050 nm. In particular, the abnormalities of the lamina cribrosa and peripapillary sclera were evaluated.
The lamina cribrosa was posteriorly displaced in all the four eyes, and the disk area was filled with herniated retinal tissue. A bump-like protrusion near the papillary margin or within the cup area was observed in three eyes. Some tissues were observed to exist between the retina and the sclera surrounding the papillary margin annularly. In one case, swept source optical coherence tomography detected intrascleral adipose tissue in a relatively wide area around the fovea and the optic nerve.
Swept source optical coherence tomography clearly delineated the papillary and peripapillary abnormalities of morning glory syndrome. Scleral structural abnormalities were present outside the optic nerve as well.
本研究旨在通过扫频源光学相干断层扫描(SS-OCT)来研究牵牛花综合征患者的深层结构异常。
使用中心波长为 1050nm 的原型扫频源光学相干断层扫描系统对 4 只眼(4 例)牵牛花综合征患者的视盘及视盘周围进行检查。特别评估了筛板和视盘周围巩膜的异常情况。
所有 4 只眼的筛板均向后移位,盘区充满了疝出的视网膜组织。在 3 只眼中观察到视盘边缘附近或杯区内有类似肿块样的突起。一些组织观察到存在于视网膜和围绕视盘边缘的巩膜之间,呈环形。在 1 例中,扫频源光学相干断层扫描在黄斑和视神经周围相对较宽的区域检测到了巩膜内脂肪组织。
扫频源光学相干断层扫描清晰地描绘了牵牛花综合征的视盘和视盘周围异常。视神经外也存在巩膜结构异常。