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标本自我采集用于 SARS-CoV-2 检测:患者表现和偏好-佐治亚州亚特兰大,2020 年 8 月至 10 月。

Specimen self-collection for SARS-CoV-2 testing: Patient performance and preferences-Atlanta, Georgia, August-October 2020.

机构信息

COVID-19 Emergency Response, Centers for Disease Control and Prevention, Atlanta, GA, United States of America.

Epidemic Intelligence Service, CDC, Atlanta, GA, United States of America.

出版信息

PLoS One. 2022 Mar 9;17(3):e0264085. doi: 10.1371/journal.pone.0264085. eCollection 2022.

DOI:10.1371/journal.pone.0264085
PMID:35263342
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8906601/
Abstract

Self-collected specimens can expand access to SARS-CoV-2 testing. At a large inner-city hospital 1,082 participants self-collected saliva and anterior nasal swab (ANS) samples before healthcare workers collected nasopharyngeal swab (NPS) samples on the same day. To characterize patient preferences for self-collection, this investigation explored ability, comfort, and ease of ANS and saliva self-collection for SARS-CoV-2 testing along with associated patient characteristics, including medical history and symptoms of COVID-19. With nearly all participants successfully submitting a specimen, favorable ratings from most participants (at least >79% in ease and comfort), and equivocal preference between saliva and ANS, self-collection is a viable SARS-CoV-2 testing option.

摘要

自我采集样本可以扩大 SARS-CoV-2 检测的范围。在一家大型市内医院,1082 名参与者在医护人员当天采集鼻咽拭子(NPS)样本之前,自行采集了唾液和前鼻拭子(ANS)样本。为了描述患者对自我采集的偏好,这项调查研究了自我采集用于 SARS-CoV-2 检测的 ANS 和唾液的能力、舒适度和便利性,以及与患者特征的相关性,包括医疗史和 COVID-19 症状。几乎所有参与者都成功提交了样本,大多数参与者(至少有 79%的人在便利性和舒适度方面)给出了良好的评价,而且在唾液和 ANS 之间存在模棱两可的偏好,因此自我采集是一种可行的 SARS-CoV-2 检测选择。

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本文引用的文献

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Effects of Patient Characteristics on Diagnostic Performance of Self-Collected Samples for SARS-CoV-2 Testing.患者特征对 SARS-CoV-2 检测自采样本诊断性能的影响。
Emerg Infect Dis. 2021;27(8):2081-2089. doi: 10.3201/eid2708.210667.
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Pre-operative COVID-19 screening: a model to provide non-discretionary care for urologic patients.术前新型冠状病毒肺炎筛查:一种为泌尿外科患者提供非酌情处理医疗服务的模式。
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Validation of self-collected buccal swab and saliva as a diagnostic tool for COVID-19.
Performance Analysis of Self-Collected Nasal and Oral Swabs for Detection of SARS-CoV-2.
自我采集鼻拭子和咽拭子用于检测新型冠状病毒2的性能分析
Diagnostics (Basel). 2022 Sep 21;12(10):2279. doi: 10.3390/diagnostics12102279.
验证自我采集的口腔拭子和唾液作为 COVID-19 的诊断工具。
Int J Infect Dis. 2021 Mar;104:255-261. doi: 10.1016/j.ijid.2020.12.080. Epub 2021 Jan 2.
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Test sensitivity is secondary to frequency and turnaround time for COVID-19 screening.新冠病毒筛查时,检测敏感性次于检测频率和周转时间。
Sci Adv. 2021 Jan 1;7(1). doi: 10.1126/sciadv.abd5393. Print 2021 Jan.
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Mass Screening of Asymptomatic Persons for Severe Acute Respiratory Syndrome Coronavirus 2 Using Saliva.使用唾液对无症状者进行严重急性呼吸综合征冠状病毒 2 的大规模筛查。
Clin Infect Dis. 2021 Aug 2;73(3):e559-e565. doi: 10.1093/cid/ciaa1388.
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Testing for Severe Acute Respiratory Syndrome-Coronavirus 2: Challenges in Getting Good Specimens, Choosing the Right Test, and Interpreting the Results.检测严重急性呼吸综合征冠状病毒 2:获取良好标本、选择正确检测方法和解读结果的挑战。
Crit Care Med. 2020 Nov;48(11):1680-1689. doi: 10.1097/CCM.0000000000004594.
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