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具有透明细胞和嗜酸性粒细胞的肉瘤样肾细胞癌:病例报告及文献复习。

Sarcomatoid renal cell carcinoma with clear cells and eosinophilia: a case report and short review of the literature.

机构信息

Intensive Care Unit, Emergency County Hospital, Arad, Romania;

出版信息

Rom J Morphol Embryol. 2021 Jul-Sep;62(3):835-839. doi: 10.47162/RJME.62.3.22.

Abstract

Sarcomatoid renal cell carcinoma (SRCC) is an aggressive form of de-differentiated renal cell carcinoma. We report a case of a 79-year-old male who presented himself to the Department of Emergency complaining of macroscopic hematuria for the last two days and a back pain located in the lumbar region persisting for around a month; there were no major changes in the initial laboratory tests. Abdominal ultrasonography identified a renal mass located in the lower pole of the left kidney. The computed tomography (CT) scan with iodine-based contrast revealed the left kidney had a complete deletion of corticomedullary differentiation and a large renal mass located in the lower pole with inhomogeneous iodophilia, which measured around about 15 cm in transversal diameter and 13.6 cm in craniocaudal diameter. Nephrectomy of the left kidney was performed. Histopathological and immunochemistry tests diagnosed a SRCC with clear cells and eosinophilia. We present these findings along with a short review of the literature.

摘要

肉瘤样肾细胞癌(SRCC)是一种去分化的肾细胞癌,具有侵袭性。我们报告了一例 79 岁男性患者,因两天来出现肉眼血尿和持续约一个月的位于腰椎区的背痛到急诊就诊;初始实验室检查无明显变化。腹部超声检查发现左肾下极有一个肾肿块。碘基造影剂增强计算机断层扫描(CT)显示左肾皮质-髓质分化完全缺失,左肾下极有一个大的肿块,不均匀碘嗜性,横径约 15 厘米,前后径 13.6 厘米。行左肾切除术。组织病理学和免疫化学检查诊断为具有透明细胞和嗜酸性粒细胞的肉瘤样肾细胞癌。我们结合文献复习介绍这些发现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec43/9019667/42adcc5aef36/RJME-62-3-835-fig1.jpg

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