Internal Medicine, UPMC, Pittsburgh, Pennsylvania, USA
Gastroenterology and Hepatology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
BMJ Case Rep. 2022 Mar 9;15(3):e249428. doi: 10.1136/bcr-2022-249428.
Crohn's disease and ulcerative colitis are inflammatory bowel diseases (IBDs) and they primarily involve the intestines and confer an increased risk of thromboembolism (TE). Here we report a case of a young man with active ulcerative colitis (UC) who presented with shortness of breath and syncope. He was found on imaging to have an extensive bilateral pulmonary embolism (PE) and right heart strain with associated pulmonary infarctions. The patient was initially managed with a heparin infusion and subsequently transitioned to a direct acting oral anticoagulant (DOAC) with clinical improvement in his symptoms.
克罗恩病和溃疡性结肠炎是炎症性肠病（IBD），主要累及肠道，并增加血栓栓塞（TE）的风险。在此，我们报告一例患有活动期溃疡性结肠炎（UC）的年轻男性，他因呼吸急促和晕厥就诊。影像学检查发现他患有广泛的双侧肺栓塞（PE）和右心劳损，并伴有肺梗死。患者最初接受肝素输注治疗，随后转为直接口服抗凝剂（DOAC）治疗，症状得到改善。
