Department of Animal Science, Faculty of Agriculture, Shahid Bahonar University of Kerman (SBUK), Kerman, Iran.
GenPhySE, Université de Toulouse, INRAE, 31326, Castanet-Tolosan, France.
Sci Rep. 2022 Mar 9;12(1):3795. doi: 10.1038/s41598-022-07767-3.
The present research has estimated the additive and dominance genetic variances of genic and intergenic segments for average daily gain (ADG), backfat thickness (BFT) and pH of the semimembranosus dorsi muscle (PHS). Further, the predictive performance using additive and additive dominance models in a purebred Piétrain (PB) and a crossbred (Piétrain × Large White, CB) pig population was assessed. All genomic regions contributed equally to the additive and dominance genetic variations and lead to the same predictive ability that did not improve with the inclusion of dominance genetic effect and inbreeding in the models. Using all SNPs available, additive genotypic correlations between PB and CB performances for the three traits were high and positive (> 0.83) and dominance genotypic correlation was very inaccurate. Estimates of dominance genotypic correlations between all pairs of traits in both populations were imprecise but positive for ADG-BFT in CB and BFT-PHS in PB and CB with a high probability (> 0.98). Additive and dominance genotypic correlations between BFT and PHS were of different sign in both populations, which could indicate that genes contributing to the additive genetic progress in both traits would have an antagonistic effect when used for exploiting dominance effects in planned matings.
本研究估计了平均日增重（ADG）、背膘厚（BFT）和半膜肌 pH 值（PHS）的基因和基因间片段的加性和显性遗传方差。此外，还评估了在纯种皮特兰猪（PB）和杂交猪（皮特兰×长白猪，CB）群体中使用加性和加性显性模型的预测性能。所有基因组区域对加性和显性遗传变异的贡献相等，导致相同的预测能力，而加入显性遗传效应和近亲繁殖并不能提高模型的预测能力。利用所有可用的 SNP，PB 和 CB 群体的三个性状之间的加性基因型相关系数很高且为正（>0.83），而显性基因型相关系数则非常不准确。在两个群体中，所有性状对之间的显性基因型相关系数估计均不准确，但在 CB 中 ADG-BFT 呈正相关，在 PB 和 CB 中 BFT-PHS 呈正相关，概率很高（>0.98）。在两个群体中，BFT 和 PHS 之间的加性和显性基因型相关系数具有不同的符号，这可能表明在两个性状中，对加性遗传进展有贡献的基因在计划交配中利用显性效应时会产生拮抗作用。
