Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Korea.
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Sci Rep. 2022 Mar 9;12(1):4165. doi: 10.1038/s41598-022-07942-6.
Although previous studies reported that chewing gum during the preoperative fasting has the benefits of alleviating anxiety and dry mouth, preoperative chewing gum has yet to be accepted as a standard practice due to conventional anesthetic custom. Our study aimed to prospectively evaluate the effects of gum chewing on preoperative anxiety and patient's discomfort in female patients undergoing gynecologic surgery. Ninety-four patients were enrolled and randomized either into conventional fasting group (control group) or chewing gum with fasting group (gum group). The control group was instructed to fast from 3 p.m. on the day before surgery. The gum group performed preoperative fasting in the same manner, but was encouraged to chew gum freely during the fasting period. The primary endpoint was the degree of preoperative anxiety. For the evaluation of preoperative anxiety, Amsterdam preoperative anxiety and information scale (APAIS) was used. Preoperative gastric fluid volume and acidity were also measured as the secondary outcomes. Preoperative anxiety using APAIS was significantly lower in the gum group compared to the control group (control group vs. gum group: 20.9 vs. 17.8, p = 0.009). However, there was no significant difference in the gastric fluid analysis between the groups. In the female patients for elective gynecologic surgery, chewing gum during the preoperative fasting period helped to alleviate preoperative anxiety without additional increase of pulmonary aspiration risks.Trial registration: KCT0004422 (05/11/2019, https://cris.nih.go.kr ; registration number).
尽管先前的研究报告称，术前禁食时咀嚼口香糖具有缓解焦虑和口干的益处，但由于传统的麻醉习惯，术前咀嚼口香糖尚未被接受为标准做法。我们的研究旨在前瞻性评估女性妇科手术患者术前咀嚼口香糖对焦虑和患者不适的影响。共纳入 94 例患者，并随机分为常规禁食组（对照组）或禁食时咀嚼口香糖组（口香糖组）。对照组指示从手术前一天下午 3 点开始禁食。口香糖组以相同的方式进行术前禁食，但鼓励在禁食期间自由咀嚼口香糖。主要终点是术前焦虑程度。使用阿姆斯特丹术前焦虑和信息量表（APAIS）评估术前焦虑。还测量了术前胃内液量和酸度作为次要结局。与对照组相比，口香糖组的 APAIS 术前焦虑明显降低（对照组 vs. 口香糖组：20.9 vs. 17.8，p = 0.009）。然而，两组之间的胃内液分析没有差异。在接受择期妇科手术的女性患者中，术前禁食期间咀嚼口香糖有助于缓解术前焦虑，而不会增加肺吸入风险。试验注册：KCT0004422（05/11/2019，https://cris.nih.go.kr；注册号）。
