Nguyen Sang Ngoc, Thi Le Huyen Thanh, Tran Tam Duc, Vu Lam Tung, Ho Tho Huu
Haiphong University of Medicine and Pharmacy, Haiphong, Vietnam.
Vietnam Military Medical University, Hanoi, Vietnam.
Int J Nephrol. 2022 Feb 28;2022:2552990. doi: 10.1155/2022/2552990. eCollection 2022.
In individuals with urinary tract infections, is an ubiquitous causative agent and antibiotic resistance is on the rise throughout the world. Therefore, early diagnosis and appropriate choice of antimicrobials are essential. The purpose of our study is to describe some of the clinical and epidemiological characteristics and the laboratory test results of children treated in our hospital for urinary tract infections caused by .
The study included 128 patients from 2 months to 15 years of age with urinary tract infections caused by and treated at the Haiphong Children's Hospital during the periods of 2011-2013 and 2018-2020.
During the two study periods, 57 and 71 cases, respectively, were included. The most common clinical symptom was fever in 40 and 46 cases, respectively. The proportion of 's resistance to ampicillin increased from 85.3% in 2011-2013 to 97.1% in 2018-2020. In 2011-2013, 70.5% of isolates were resistant to cotrimoxazole, which increased to 81.4% during 2018-2020. During both periods, was highly sensitive to amikacin, at 87% and 95.5%, respectively. In 2018-2020, carbapenems (meropenem and imipenem) and piperacillin were also effective against .
Our study revealed that high fever was the most prevalent clinical characteristic in urinary tract infections caused by in children and was mostly resistant to ampicillin, nalidixic acid, and cotrimoxazole but was highly sensitive to ciprofloxacin, amikacin, piperacillin, meropenem, and imipenem.
在患有尿路感染的个体中，是一种普遍存在的病原体，并且抗生素耐药性在全球范围内呈上升趋势。因此，早期诊断和适当选择抗菌药物至关重要。我们研究的目的是描述在我院接受治疗的由引起的儿童尿路感染的一些临床和流行病学特征以及实验室检查结果。
该研究纳入了2011 - 2013年以及2018 - 2020年期间在海防儿童医院接受治疗的128例年龄在2个月至15岁之间、由引起的尿路感染患者。
在两个研究期间，分别纳入了57例和71例病例。最常见的临床症状分别是40例和46例发热。对氨苄西林的耐药率从2011 - 2013年的85.3%上升至2018 - 2020年的97.1%。在2011 - 2013年，70.5%的分离株对复方新诺明耐药，在2018 - 2020年期间这一比例升至81.4%。在两个时期，对阿米卡星均高度敏感，分别为87%和95.5%。在2018 - 2020年，碳青霉烯类（美罗培南和亚胺培南）以及哌拉西林对也有效。
我们的研究表明，高热是儿童由引起的尿路感染中最普遍的临床特征，并且对氨苄西林、萘啶酸和复方新诺明大多耐药，但对环丙沙星、阿米卡星、哌拉西林、美罗培南和亚胺培南高度敏感。
