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巴格达市儿童中央教学医院儿童尿路感染的致病微生物及耐药性

Causative organism of urinary tract infection and drug resistance in children at child's Central Teaching Hospital in Baghdad City.

作者信息

Abdul Raheem Rasha Sulaiman, Hussein Mushriq Abdullah, Al-Din Noor Issam

机构信息

Department of Paediatrics, Al-Mustansiriya University, Baghdad, Iraq.

出版信息

J Pak Med Assoc. 2019 Aug;69(Suppl 3)(8):S59-S63.

PMID:31603879
Abstract

OBJECTIVE

To identify antibiotic susceptibility and resistance of bacterial strains responsible for urinary tract infections in children.

METHODS

The cross-sectional study was conducted from June to December 2017 at the Central Teaching Hospital, Baghdad, Iraq, and comprised patients aged between one day and 15 years who were brought to the emergency department and were diagnosed as having urinary tract infections. Urine samples were cultured on appropriate media and the isolated organisms were identified. The susceptibility of bacteria-causing urinary tract infection to different antimicrobial agents was investigated using antibiotic discs. Data was analysed using SPSS 24.

RESULTS

Of the 155 patients, 78(50.3%) were girls and 77(49.7%) were boys. The highest number of patients 55(35.5%) were aged <1 year. The most common organism encountered in the study were Escherichia coli 78(50.followed by Klebsiella pneumonia 21(13.5%). Among the Escherichia coli isolates,54(69.2%) were resistant to ceftriaxone, 50(64.1%)to ampicillin and 38(48.7%) to ciprofloxacin.

CONCLUSIONS

Escherichia coli was found to be most predominant organism causing urinary tract infection, and it was resistant, among others, to ceftriaxone, ampicillin and ciprofloxacin.

摘要

目的

确定引起儿童尿路感染的细菌菌株的抗生素敏感性和耐药性。

方法

2017年6月至12月在伊拉克巴格达中央教学医院进行了一项横断面研究,研究对象为年龄在1天至15岁之间、被送往急诊科且被诊断为尿路感染的患者。将尿液样本接种在合适的培养基上,对分离出的微生物进行鉴定。使用抗生素纸片研究引起尿路感染的细菌对不同抗菌药物的敏感性。使用SPSS 24对数据进行分析。

结果

155例患者中,78例(50.3%)为女孩,77例(49.7%)为男孩。患者数量最多的是55例(35.5%)年龄<1岁。研究中最常见的微生物是大肠埃希菌78例(50.3%),其次是肺炎克雷伯菌21例(13.5%)。在大肠埃希菌分离株中,54例(69.2%)对头孢曲松耐药,50例(64.1%)对氨苄西林耐药,38例(48.7%)对环丙沙星耐药。

结论

发现大肠埃希菌是引起尿路感染最主要的微生物,并且它对头孢曲松、氨苄西林和环丙沙星等耐药。

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