Al Alwan Ibrahim, Al Issa Nouf, Al Anazi Yousef, Al Noaim Khalid, Mughal M Zulf, Babiker Amir
College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
Endocrine Division, Department of Pediatrics, King Abdullah Specialized Children Hospital, Riyadh, Saudi Arabia.
Case Rep Endocrinol. 2022 Feb 27;2022:7072815. doi: 10.1155/2022/7072815. eCollection 2022.
Vitamin D intoxication (VDI) usually develops due to inappropriate use of vitamin D in high doses by the families of infants with complaints suggestive of vitamin D deficiency such as delayed teething, knock knees, or delayed walking. We present here an experience of treating an infant with asymptomatic VDI that had a prolonged course of recovery and a sustainable level of vitamin D over a follow-up period of 2.5 years. In our patient, vitamin D started to drop steadily after a month of stopping vitamin D supplements but not to a normal level. It reached an acceptable level only after six months. This case emphasizes the importance of educating parents about the empirical use of vitamin D over the counter, assessing the baseline level of serum vitamin D level prior to initiation of treatment and highlights the value of verifying additional dietary sources of vitamin D or oral supplements in patient's history.
维生素D中毒(VDI)通常是由于有出牙延迟、膝外翻或行走延迟等提示维生素D缺乏症状的婴儿家庭不恰当地大剂量使用维生素D所致。我们在此介绍一例无症状VDI婴儿的治疗经历,该婴儿恢复过程漫长,在2.5年的随访期内维生素D水平持续稳定。在我们的患者中,停用维生素D补充剂一个月后,维生素D开始稳步下降,但未降至正常水平。直到六个月后才达到可接受水平。该病例强调了对家长进行非处方维生素D经验性使用教育的重要性,在开始治疗前评估血清维生素D水平的基线水平,并突出了核实患者病史中维生素D的其他饮食来源或口服补充剂的价值。