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利用改进的正交方法平衡心脏电生理学中的传导速度误差。

Balancing conduction velocity error in cardiac electrophysiology using a modified quadrature approach.

机构信息

Institute for Structural Analysis, Technische Universität Dresden, Dresden, Germany.

出版信息

Int J Numer Method Biomed Eng. 2022 May;38(5):e3589. doi: 10.1002/cnm.3589. Epub 2022 Mar 25.

Abstract

Conduction velocity error is often the main culprit behind the need for very fine spatial discretizations and high computational effort in cardiac electrophysiology problems. In light of this, a novel approach for simulating an accurate conduction velocity in coarse meshes with linear elements is suggested based on a modified quadrature approach. In this approach, the quadrature points are placed at arbitrary offsets of the isoparametric coordinates. A numerical study illustrates the dependence of the conduction velocity on the spatial discretization and the conductivity when using different quadrature rules and calculation approaches. Additionally, examples using the modified quadrature in coarse meshes for wave propagation demonstrate the improved accuracy of the conduction velocity with this method. This novel approach possesses great potential in reducing the computational effort required but remains limited to specific linear elements and experiences a reduction in accuracy for irregular meshes and heterogeneous conductivities. Further research can focus on developing an adaptive quadrature and extending the approach to other element formulations in order to make the approach more generally applicable.

摘要

传导速度误差往往是心脏电生理学问题需要非常精细的空间离散化和高计算量的主要原因。有鉴于此,本文提出了一种基于修正求积法的新方法,用于在具有线性元的粗网格中模拟准确的传导速度。在该方法中,求积点位于等参坐标的任意偏移处。数值研究说明了在使用不同的求积规则和计算方法时,传导速度对空间离散化和电导率的依赖性。此外,使用粗网格中的修正求积进行波传播的示例表明,该方法可以提高传导速度的准确性。这种新方法在降低计算工作量方面具有很大的潜力,但仍然限于特定的线性元,并且在不规则网格和非均匀电导率下准确性会降低。进一步的研究可以集中于开发自适应求积并将该方法扩展到其他元素公式,以使该方法更具通用性。

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