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沙特患对皮质类固醇无反应的肾病综合征儿童的肾活检:初步报告。

Renal biopsy in Saudi children with nephrotic syndrome not responsive to corticosteroid: a preliminary report.

作者信息

Abdurrahman M B, el-Idrissy A T, Hafeez M A, Wright E A, Omar S A

出版信息

Trop Geogr Med. 1986 Jun;38(2):141-5.

PMID:3526671
Abstract

Percutaneous renal biopsy was done in 25 Saudi children whose nephrotic syndrome did not respond to prednisolone. The histologic diagnosis was mesangial proliferative glomerulonephritis in 11 cases; an additional two biopsies had features of both mesangial proliferative glomerulonephritis and focal segmental glomerulosclerosis. Immunofluorescence was abnormal in 16 out of 21 patients, with IgM as the most frequently detected immunogen.

摘要

对25名沙特儿童进行了经皮肾活检,这些儿童的肾病综合征对泼尼松龙无反应。组织学诊断为系膜增生性肾小球肾炎11例;另外两份活检标本具有系膜增生性肾小球肾炎和局灶节段性肾小球硬化的特征。21例患者中有16例免疫荧光异常,IgM是最常检测到的免疫原。

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