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单细胞RNA测序揭示乳腺癌中异质性循环肿瘤细胞亚群

Single-Cell RNA Sequencing Uncovers Heterogeneous Circulating Tumor Cell Subsets in Breast Cancer.

作者信息

Papadaki Maria A, Agelaki Sofia

机构信息

Laboratory of Translational Oncology, School of Medicine, University of Crete, 70013 Heraklion, Greece.

Department of Medical Oncology, University General Hospital of Heraklion, 71110 Heraklion, Greece.

出版信息

Cancers (Basel). 2022 Mar 4;14(5):1314. doi: 10.3390/cancers14051314.

DOI:10.3390/cancers14051314
PMID:35267622
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8909171/
Abstract

Metastasis remains the main cause of death for breast cancer (BC) patients, and conceivably, a huge effort has been directed toward the understanding of the metastatic process [...].

摘要

转移仍然是乳腺癌（BC）患者死亡的主要原因，可以想象，人们已经付出了巨大努力来了解转移过程[……]。

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Single-Cell RNA Sequencing Uncovers Heterogeneous Circulating Tumor Cell Subsets in Breast Cancer.单细胞RNA测序揭示乳腺癌中异质性循环肿瘤细胞亚群
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引用本文的文献

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本文引用的文献

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TLR4 and pSTAT3 Expression on Circulating Tumor Cells (CTCs) and Immune Cells in the Peripheral Blood of Breast Cancer Patients: Prognostic Implications.乳腺癌患者外周血中循环肿瘤细胞（CTC）和免疫细胞上的TLR4与pSTAT3表达：预后意义
Cancers (Basel). 2022 Feb 18;14(4):1053. doi: 10.3390/cancers14041053.
2
Transcriptomic profiling of single circulating tumor cells provides insight into human metastatic gastric cancer.单细胞循环肿瘤细胞的转录组谱分析为人类转移性胃癌提供了新见解。
Commun Biol. 2022 Jan 11;5(1):20. doi: 10.1038/s42003-021-02937-x.
3
Circulating Tumor Cell Transcriptomics as Biopsy Surrogates in Metastatic Breast Cancer.循环肿瘤细胞转录组学作为转移性乳腺癌的活检替代物。
Ann Surg Oncol. 2022 May;29(5):2882-2894. doi: 10.1245/s10434-021-11135-2. Epub 2022 Jan 9.
4
Heterogeneity of Circulating Tumor Cell Neoplastic Subpopulations Outlined by Single-Cell Transcriptomics.单细胞转录组学勾勒出的循环肿瘤细胞肿瘤亚群的异质性
Cancers (Basel). 2021 Sep 29;13(19):4885. doi: 10.3390/cancers13194885.
5
Epithelial-to-mesenchymal Transition Heterogeneity of Circulating Tumor Cells and Their Correlation With MDSCs and Tregs in HER2-negative Metastatic Breast Cancer Patients.循环肿瘤细胞上皮-间充质转化异质性及其与 HER2 阴性转移性乳腺癌患者骨髓来源抑制性细胞和调节性 T 细胞的相关性。
Anticancer Res. 2021 Feb;41(2):661-670. doi: 10.21873/anticanres.14817.
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Cancers (Basel). 2020 Dec 11;12(12):3735. doi: 10.3390/cancers12123735.
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Cancers (Basel). 2020 Jun 12;12(6):1556. doi: 10.3390/cancers12061556.
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