Department of Surgery, Seoul St. Mary's Hospital, Banpo-daero 222, Seocho-gu, Seoul 06591, Korea.
Department of Surgery, Division of Trauma and Surgical Critical Care, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Banpo-daero 222, Seocho-gu, Seoul 06591, Korea.
Nutrients. 2022 Feb 23;14(5):946. doi: 10.3390/nu14050946.
For patients undergoing abdominal surgery, malnutrition further increases the susceptibility to infection, surgical complications, and mortality. However, there is no standard tool for identifying high-risk groups of malnutrition or exact criteria for the optimal target of nutrition supply. We aimed to identify the nutritional risk in critically ill patients using modified Nutrition Risk in the Critically Ill (mNUTRIC) scores and assessing the relationship with clinical outcomes. Furthermore, we identified the ideal target of energy intake during the acute postoperative period. A prospective observational study was conducted. mNUTRIC scores and the average calories prescribed and given were calculated. To identify the high-risk group of malnutrition, receiver operating characteristic curves were plotted. The ideal target of energy adequacy and predisposing factors of 90-day mortality were assessed using multiple logistic regression analyses. A total of 206 patients were analyzed. The cutoff value for mNUTRIC score predicting 90-day mortality was 5 (Area under the curve = 0.7, 95% confidence interval (Cl) 0.606−0.795, p < 0.001). A total of 75 patients (36.4%) were classified in the high mNUTRIC group (mNUTRIC ≥ 5) and had a significantly higher postoperative complication and longer length of surgical intensive care unit stay. High mNUTRIC scores (odds ratio = 2.548, 95% CI 1.177−5.514, p = 0.018) and energy adequacy less than 50% (odds ratio = 6.427, 95% CI 1.674−24.674, p = 0.007) were associated with 90-day mortality.
对于接受腹部手术的患者,营养不良会进一步增加感染、手术并发症和死亡率的风险。然而,目前尚无用于识别营养不良高危人群或确定最佳营养供应目标的确切标准的工具。我们旨在使用改良的危重症患者营养风险评分(mNUTRIC)识别危重症患者的营养风险,并评估其与临床结局的关系。此外,我们确定了急性术后期间能量摄入的理想目标。进行了一项前瞻性观察性研究。计算了 mNUTRIC 评分和规定及给予的平均卡路里数。为了确定营养不良的高风险人群,绘制了受试者工作特征曲线。使用多因素逻辑回归分析评估了能量充足的理想目标和 90 天死亡率的易患因素。共分析了 206 例患者。预测 90 天死亡率的 mNUTRIC 评分截断值为 5(曲线下面积为 0.7,95%置信区间为 0.606−0.795,p < 0.001)。共有 75 例患者(36.4%)被归类为高 mNUTRIC 组(mNUTRIC ≥ 5),术后并发症发生率更高,且外科重症监护病房住院时间更长。高 mNUTRIC 评分(比值比=2.548,95%置信区间为 1.177−5.514,p = 0.018)和能量摄入不足 50%(比值比=6.427,95%置信区间为 1.674−24.674,p = 0.007)与 90 天死亡率相关。