Department of Surgery, School of Medicine, Ajou University, Suwon 16499, Korea.
Department of Surgery, Yonsei University College of Medicine, Seoul 03722, Korea.
Nutrients. 2018 Oct 29;10(11):1589. doi: 10.3390/nu10111589.
Modified NUTRIC (mNUTRIC) score is a useful assessment tool to determine the risk of malnutrition in patients on mechanical ventilation (MV). We identified associations between postoperative calorie adequacy, 30-day mortality, and surgical outcomes in patients with high mNUTRIC scores. Medical records of 272 patients in the intensive care unit who required MV support for >24 h after emergency gastro-intestinal (GI) surgery between January 2007 and December 2017 were reviewed. Calorie adequacy in percentage (Calorie intake in 5 days ÷ Calorie requirement for 5 days × 100) was assessed in patients with high (5⁻9) and low (0⁻4) mNUTRIC scores. In the high mNUTRIC score group, patients with inadequate calorie supplementation (calorie adequacy <70%) had higher 30-day mortality than those with adequate supplementation (31.5% vs. 11.1%; 0.010); this was not observed in patients with low mNUTRIC scores. This result was also confirmed through Kaplan⁻Meier survival curve ( = 0.022). Inadequate calorie supplementation in the high mNUTRIC score group was not associated with Intra-abdominal infection ( = 1.000), pulmonary complication ( = 0.695), wound complication ( = 0.407), postoperative leakage ( = 1.000), or infections ( = 0.847). Inadequate calorie supplementation after GI surgery was associated with higher 30-day mortality in patients with high mNUTRIC scores. Therefore, adequate calorie supplementation could contribute to improved survival of critically ill postoperative patients with high risk of malnutrition.
改良 NUTRIC(mNUTRIC)评分是评估机械通气(MV)患者营养不良风险的有用工具。我们发现高 mNUTRIC 评分患者的术后热量充足程度、30 天死亡率和手术结果之间存在关联。回顾了 2007 年 1 月至 2017 年 12 月间因急症胃肠(GI)手术后需要 MV 支持>24 小时而入住重症监护病房的 272 名患者的病历。评估了高(5-9)和低(0-4)mNUTRIC 评分患者的热量充足程度(5 天的热量摄入÷5 天的热量需求×100)。在高 mNUTRIC 评分组中,热量补充不足(热量充足度<70%)的患者 30 天死亡率高于热量补充充足的患者(31.5%比 11.1%;0.010);而低 mNUTRIC 评分组的患者则没有观察到这种情况。这一结果也通过 Kaplan-Meier 生存曲线得到了证实(=0.022)。高 mNUTRIC 评分组中热量补充不足与腹腔内感染(=1.000)、肺部并发症(=0.695)、伤口并发症(=0.407)、术后漏液(=1.000)或感染(=0.847)无关。因此,高 mNUTRIC 评分患者 GI 手术后热量补充不足与 30 天死亡率升高有关。因此,充足的热量补充可能有助于改善高营养不良风险的危重症术后患者的生存。