Departamento de Genética y Biología Molecular, Cinvestav, Avenida IPN 2508, Ciudad de Mexico 07360, Mexico.
Departamento de Salud, Universidad Iberoamericana, Ciudad de México, Paseo de la Reforma 880, Ciudad de Mexico 01219, Mexico.
Nutrients. 2022 Feb 27;14(5):1008. doi: 10.3390/nu14051008.
Obesity is a multifactorial disease resulting in excessive accumulation of fat. Worldwide, obesity is an important public health problem, affecting a large proportion of the world population. The tender cactus , commonly known in Mexico as "nopal", is widely distributed in this country, Latin America, South Africa, and the Mediterranean area. Nopal cladodes are commonly marketed in different forms as fresh, frozen, or pre-cooked, and used as fresh green vegetable. The aim of this study was to evaluate the capability of nopal to improve the health condition of participants affected by obesity, in a physical and dietary intervention, through gut microbiota modification. These results were contrasted with the effect of nopal in the gut microbiota of normal weight participants. We describe the association among biochemical, anthropometric markers, and the gut microbiota diversity found in fecal samples of the obese and normal weight groups. The results presented in this work suggest that caloric restriction, addition of nopal to the diet and physical activity, promote changes in the gut microbiota in obese women, improving the host metabolism, as suggested by the correlation between some bacterial species with biochemical and anthropometrical parameters.
肥胖是一种多因素疾病，导致脂肪过度积累。在全球范围内，肥胖是一个重要的公共卫生问题，影响了世界上很大一部分人口。仙人掌，在墨西哥通常被称为“龙舌兰”，广泛分布在这个国家、拉丁美洲、南非和地中海地区。龙舌兰的嫩茎通常以新鲜、冷冻或预先煮熟的形式在不同的形式下销售，并用作新鲜的绿色蔬菜。本研究的目的是评估龙舌兰通过改变肠道微生物群来改善肥胖参与者的健康状况的能力，这种干预措施包括身体和饮食干预。我们将龙舌兰对正常体重参与者肠道微生物群的影响与这些结果进行了对比。我们描述了肥胖组和正常体重组粪便样本中生化、人体测量标志物和肠道微生物多样性之间的关联。本工作中的结果表明，热量限制、在饮食中添加龙舌兰和体育活动促进了肥胖女性肠道微生物群的变化，改善了宿主的新陈代谢，这可以通过一些细菌物种与生化和人体测量参数之间的相关性来证明。
