Suzuki A, Ito S, Takechi H
Acta Med Okayama. 1986 Jun;40(3):147-61. doi: 10.18926/AMO/31936.
A series of clinical and pathological studies were performed on 74 cartilaginous bone tumors including osteochondromas, multiple cartilaginous exostoses, chondromas, chondromatoses, benign chondroblastomas and chondrosarcomas. Resection was adequate for the osteochondromas, and no recurrence was observed. Out of 14 multiple cartilaginous exostoses, three, all in flat bones showed malignant change. The predominant sites of chondroma were the finger and toe bones, and curettage and bone graft was adequate treatment. Neither recurrence nor malignant change was observed. Two cases of chondromatosis, one of Ollier's disease and one of Maffucci's syndrome, were included in our series. Leg length discrepancy and pathologic fracture were common problems in chondromatosis. Moreover, malignant change was suspected in a hemangioma of the Maffucci's syndrome patient. Benign chondroblastoma was treated by curettage and bone graft, with no recurrence. In our series, 4 primary and 3 secondary chondrosarcomas were observed. Metastasis was seen in only one case. Because of the discrepancy between the biological behavior and histological findings of cartilaginous bone tumors, the malignancy of tumors should be evaluated by clinical signs and symptoms as well as by histological findings.
对74例软骨性骨肿瘤进行了一系列临床和病理研究，这些肿瘤包括骨软骨瘤、多发性软骨外生骨疣、软骨瘤、软骨瘤病、良性软骨母细胞瘤和软骨肉瘤。骨软骨瘤切除充分，未观察到复发。在14例多发性软骨外生骨疣中，3例发生于扁骨的病例出现了恶变。软骨瘤的主要部位是手指和脚趾骨，刮除术和骨移植是充分的治疗方法。未观察到复发或恶变。我们的系列研究纳入了2例软骨瘤病病例，1例为奥利尔病，1例为马富西综合征。肢体长度差异和病理性骨折是软骨瘤病的常见问题。此外，怀疑马富西综合征患者的1例血管瘤发生了恶变。良性软骨母细胞瘤采用刮除术和骨移植治疗，无复发。在我们的系列研究中，观察到4例原发性和3例继发性软骨肉瘤。仅1例出现转移。由于软骨性骨肿瘤的生物学行为和组织学表现之间存在差异，肿瘤的恶性程度应通过临床体征和症状以及组织学表现来评估。
