Semenova L A, Bulycheva I V
Arkh Patol. 2007 Sep-Oct;69(5):45-8.
Chondromas combine a group of benign cartilaginous tissue tumors with common histological manifestations. The tumors (enchondroma, periosteal chondroma, and enchondromatosis) differ in sites and clinical manifestations. Chondromas are generally hypocellular, avascular tumors with an abundance of hyaline cartilage matrix and chondrocytes located diffusely, in clones or lobules. Small bone chondromas, Ollier's disease, and Mafucci's syndrome are characterized by the tumor tissue containing a large number of cells and by greater cytological atypia. Enchondroma is successfully treated by surgical methods.
软骨瘤是一组具有共同组织学表现的良性软骨组织肿瘤。这些肿瘤(内生软骨瘤、骨膜软骨瘤和内生软骨瘤病)在部位和临床表现上有所不同。软骨瘤通常是细胞稀少、无血管的肿瘤,有大量透明软骨基质,软骨细胞呈弥漫性、克隆性或小叶状分布。小骨软骨瘤、Ollier病和Mafucci综合征的特点是肿瘤组织含有大量细胞且细胞异型性更大。内生软骨瘤通过手术方法可成功治疗。