Molini Umberto, Coetzee Lauren Michelle, Van Zyl Leandra, Khaiseb Siegfried, Cattoli Giovanni, Dundon William G, Franzo Giovanni
School of Veterinary Medicine, Faculty of Health Sciences and Veterinary Medicine, Neudamm Campus, University of Namibia, Private Bag 13301, Windhoek 9000, Namibia.
Central Veterinary Laboratory (CVL), 24 Goethe Street, Private Bag 18137, Windhoek 9000, Namibia.
Animals (Basel). 2022 Mar 1;12(5):620. doi: 10.3390/ani12050620.
Members of the genus Circovirus have been identified in several host species. While initially considered host-specific, there is growing evidence of their presence in unexpected hosts. Porcine circovirus 2 (PCV-2) is no exception, having been reported in animals belonging to different orders, including carnivores. Recently, PCV-2 was detected in domestic pigs, warthogs and antelopes in Namibia. Considering the potential contact between these populations and wild carnivores, the presence of PCV-2 was investigated in 32 black-backed jackals () shot between February and July 2021 as part of predator control operations in Namibia. Two lung lymph nodes tested positive for PCV-2 by PCR, confirming the broader-than-expected PCV-2 host tropism and the susceptibility of canids. Sequence analysis demonstrated a close association between the PCV-2s identified in the jackals and PCV-2b strains collected from South African domestic pigs. Although several hypotheses regarding the source of the jackal's infection are proposed, further studies should be performed to properly assess how PCV-2 is acquired and maintained in the wild and its potential impact on wild and domestic species.
圆环病毒属的成员已在多种宿主物种中被鉴定出来。虽然最初认为它们具有宿主特异性,但越来越多的证据表明它们存在于意想不到的宿主中。猪圆环病毒2型(PCV - 2)也不例外,已在包括食肉动物在内的不同目动物中被报道。最近,在纳米比亚的家猪、疣猪和羚羊中检测到了PCV - 2。考虑到这些种群与野生食肉动物之间的潜在接触,作为纳米比亚捕食者控制行动的一部分,对2021年2月至7月间射杀的32只黑背胡狼进行了PCV - 2检测。通过PCR检测,两个肺淋巴结的PCV - 2呈阳性,证实了PCV - 2的宿主嗜性比预期更广以及犬科动物对其易感。序列分析表明,在胡狼中鉴定出的PCV - 2与从南非家猪中收集的PCV - 2b毒株密切相关。尽管提出了几种关于胡狼感染源的假设,但仍需进一步研究,以正确评估PCV - 2在野外是如何获得和维持的,以及它对野生和家养物种的潜在影响。