Xu Min, Tan Weiguo, Wang Wenhua, Wang Dongdong, Zeng Wei, Wang Cunzu
Department of Neurosurgery, Kunshan Hospital of Traditional Chinese Medicine (Kunshan Affiliated Hospital of Nanjing University of Chinese Medicine), Kunshan 215300, China.
Department of Neurosurgery, Northern Jiangsu People's Hospital, Yangzhou 225001, China.
J Clin Med. 2022 Feb 28;11(5):1321. doi: 10.3390/jcm11051321.
Objective: To investigate the effects of minimally invasive surgery (MIS) using a novel YL-1 puncture needle and summarize the risk factors of recurrence in chronic subdural hematoma (CSDH). Methods: We performed a retrospective analysis in 516 hospitalized patients with CSDH from January 2013 to December 2018 in Northern Jiangsu People’s Hospital. Patients’ gender, age, history of trauma, use of anticoagulants, history of disturbed liver or renal function, history of heart disease, history of malignant tumor, history of diabetes, hemodialysis, coagulopathy, alcoholism, imaging indicators, and postoperative application of urokinase or atorvastatin were recorded. Recurrence is defined by imaging examination with or without clinical presentation three months after discharge. Results: In total, 483 patients (93.60%) benefited from MIS by YL-1 needle. Gender, age, history of head trauma, history of disturbed liver function, history of heart disease, history of malignant tumor, history of diabetes, history of hemodialysis, coagulopathy, alcoholism, hematoma location, hematoma densities, septum formation, maximum thickness, encephalatrophy, and use of atorvastatin and urokinase were shown to be non-significantly associated with postoperative recurrence (p > 0.05). The use of anticoagulants was significantly associated with postoperative recurrence (p > 0. 05). Logistic analysis showed that the use of anticoagulants is an independent factor predicting postoperative recurrence (p > 0. 05). Conclusions: The novel YL-1 puncture needle turned out to be a safe and effective minimally invasive surgery, and the use of anticoagulants is an independent risk factor predicting postoperative recurrence in CSDH, which can provide MIS and early therapeutic strategies for neurosurgeons.
探讨使用新型YL-1穿刺针进行微创手术(MIS)的效果,并总结慢性硬膜下血肿(CSDH)复发的危险因素。方法:我们对2013年1月至2018年12月在苏北人民医院住院的516例CSDH患者进行了回顾性分析。记录患者的性别、年龄、外伤史、抗凝剂使用情况、肝功能或肾功能紊乱史、心脏病史、恶性肿瘤史、糖尿病史、血液透析、凝血功能障碍、酗酒、影像学指标以及术后尿激酶或阿托伐他汀的应用情况。复发定义为出院后三个月影像学检查有或无临床表现。结果:总共483例患者(93.60%)通过YL-1针进行的MIS获得了良好效果。性别、年龄、头部外伤史、肝功能紊乱史、心脏病史、恶性肿瘤史、糖尿病史、血液透析史、凝血功能障碍、酗酒、血肿位置、血肿密度、隔膜形成、最大厚度、脑萎缩以及阿托伐他汀和尿激酶的使用与术后复发无显著相关性(p>0.05)。抗凝剂的使用与术后复发显著相关(p<0.05)。Logistic分析显示,抗凝剂的使用是预测术后复发的独立因素(p<0.05)。结论:新型YL-1穿刺针是一种安全有效的微创手术,抗凝剂的使用是预测CSDH术后复发的独立危险因素,可为神经外科医生提供微创手术及早期治疗策略。