Department of Neurosurgery, Kunshan Hospital of Traditional Chinese Medicine, Kunshan Affiliated Hospital of Nanjing University of Chinese Medicine, Kunshan, 215300, Jiangsu, China.
Acta Neurol Belg. 2020 Feb;120(1):37-42. doi: 10.1007/s13760-018-0914-z. Epub 2018 Apr 5.
The objective of this study is to investigate effects of minimally invasive approaches on outcome of chronic subdural hematoma (CSDH) by novel YL-1 puncture needle and burr-hole methods. A retrospective analysis was performed in 158 hospitalized CSDH patients from January, 2013 to December, 2017 in Kunshan Hospital of Traditional Chinese Medicine. Patients' gender, age, history of trauma, volume of hematoma, hematoma location, application of urokinase, surgical approach, the operation time, hospitalized time, and CT scans 3 months after discharge were recorded. Prognostic indicators including symptom relief and post-hospital neuro-imaging findings were extracted to evaluate surgical efficacy. Statistical methods were conducted to evaluate surgical efficacy. Both YL-1 puncture needle and burr-hole surgeries had a satisfying follow-up (93.67%). There was non-significant group difference in follow-up results (p > 0.05). While YL-1 needle group needs less operation time ((p < 0.001) and hospitalized time (p < 0.001), gender (p = 0.144), age (p = 0.394), history of head trauma (p = 0.445), volume of hematoma (p = 0.068), hematoma location (p = 0.281), and application of urokinase (p = 0.545) were shown non-significantly associated with these two minimally invasive approaches. Volume of hematoma was significantly associated with follow-up outcomes (p = 0.016). Novel YL-1 puncture needle and classic burr-hole craniotomy are both proved to be safe and effective minimally invasive surgeries, which can provide an early intervention and minimally invasive strategy for neurosurgeons.
本研究旨在通过新型 YL-1 穿刺针和颅骨钻孔方法探讨微创方法对慢性硬脑膜下血肿(CSDH)结局的影响。回顾性分析 2013 年 1 月至 2017 年 12 月在昆山市中医院住院的 158 例 CSDH 患者。记录患者性别、年龄、外伤史、血肿量、血肿位置、尿激酶应用、手术方式、手术时间、住院时间,以及出院后 3 个月的 CT 扫描。提取预后指标,包括症状缓解和出院后神经影像学检查结果,以评估手术疗效。采用统计学方法评估手术疗效。YL-1 穿刺针和颅骨钻孔手术均有满意的随访(93.67%)。两组随访结果无显著性差异(p>0.05)。虽然 YL-1 针组的手术时间(p<0.001)和住院时间(p<0.001)较短,但性别(p=0.144)、年龄(p=0.394)、头部外伤史(p=0.445)、血肿量(p=0.068)、血肿位置(p=0.281)和尿激酶应用(p=0.545)无显著性差异。血肿量与随访结果显著相关(p=0.016)。新型 YL-1 穿刺针和经典颅骨钻孔术均为安全有效的微创术式,可为神经外科医生提供早期干预和微创策略。