Fuentes-Alonso Marta, Jimenez-Garcia Rodrigo, Lopez-de-Andres Ana, Zamorano-Leon Jose J, Carabantes-Alarcon David, Jimenez-Trujillo Isabel, Sanz-Rojo Sara, de Miguel-Diez Javier
Respiratory Department, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Universidad Complutense de Madrid, 28040 Madrid, Spain.
Department of Public Health & Maternal and Child Health, Faculty of Medicine, Universidad Complutense de Madrid, IdISSC, 28040 Madrid, Spain.
J Clin Med. 2022 Mar 4;11(5):1423. doi: 10.3390/jcm11051423.
(1) Background: To analyze time trends, sex differences, and factors associated with influenza vaccination uptake among individuals with COPD in Spain, 2012−2020. (2) Methods: A cross-sectional study based on data from the European Health Surveys for Spain, 2020 (EHSS2020) and 2014 and from the Spanish National Health Interview Surveys for 2017 and 2012. (3) Results: The study included 65,447 participants. Prevalence of COPD was 5.9% (n = 3855). Overall, the influenza vaccination uptake among COPD patients was 57.8% versus 28.6% for those without COPD (p < 0.001). Men with COPD reported higher uptake than women in all the surveys studied. Neither the crude nor the multivariable analysis showed a significant variation change overtime for people with COPD. However, among those aged <65 years, crude uptake decreased from 2012 to 2020 (39.4% vs. 33.3%; p = 0.039). Over the entire period, men were vaccinated significantly more than women (OR 1.28; 95% CI 1.12−1.47). Among COPD participants, included in the EHSS2020, independent predictors of vaccine uptake included being male, higher age, reporting no current smoking and suffering cancer or heart disease. (4) Conclusions: In COPD patients, the influenza vaccination uptake is below desirable levels and did not improve from 2012 to 2020. Sex differences are found, with consistent and constant lower uptake among women with COPD. The observed lower uptake among COPD women and patients with unhealthy lifestyle requires increased attention.
(1) 背景：分析2012 - 2020年西班牙慢性阻塞性肺疾病（COPD）患者流感疫苗接种的时间趋势、性别差异及相关因素。(2) 方法：基于2020年（EHSS2020）和2014年西班牙欧洲健康调查以及2017年和2012年西班牙国民健康访谈调查的数据进行横断面研究。(3) 结果：该研究纳入65447名参与者。COPD患病率为5.9%（n = 3855）。总体而言，COPD患者的流感疫苗接种率为57.8%，而无COPD者为28.6%（p < 0.001）。在所有研究的调查中，患有COPD的男性报告的接种率高于女性。COPD患者的粗率分析和多变量分析均未显示随时间有显著变化。然而，在年龄<65岁的人群中，2012年至2020年粗接种率有所下降（39.4%对33.3%；p = 0.039）。在整个期间，男性接种疫苗的比例显著高于女性（OR 1.28；95% CI 1.12 - 1.47）。在纳入EHSS2020的COPD参与者中，疫苗接种的独立预测因素包括男性、年龄较大、报告目前不吸烟以及患有癌症或心脏病。(4) 结论：在COPD患者中，流感疫苗接种率低于理想水平，且2012年至2020年未有所改善。发现存在性别差异，COPD女性的接种率持续且始终较低。COPD女性和生活方式不健康的患者中观察到的较低接种率需要更多关注。
Zotero 插件