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技术辅助平衡训练在帕金森病中的可接受性和初步结果。

Acceptability and Preliminary Results of Technology-Assisted Balance Training in Parkinson's Disease.

机构信息

Scientific Direction, IRCCS INRCA, 60124 Ancona, Italy.

Clinical Unit of Physical Rehabilitation, IRCCS INRCA, 63900 Fermo, Italy.

出版信息

Int J Environ Res Public Health. 2022 Feb 24;19(5):2655. doi: 10.3390/ijerph19052655.

DOI:10.3390/ijerph19052655
PMID:35270348
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8910202/
Abstract

(1) Background: Parkinson's Disease (PD) is one of the most common causes of disability among older individuals. The advanced stages of PD are usually characterized by postural instability and, as a consequence, falls. Those are among the main factors that determine the quality of life, as well as the morbidity and mortality of a person with PD. In the field of PD rehabilitation, robotics is also rapidly gaining ground. As a primary aim, we evaluate the acceptability of the technology integrated intervention, using the Psychosocial Impact of Assistive Devices Scale (PIADS), in order to analyze the attitude of the participants towards the Tymo system. As a secondary outcome, we assess the result of the rehabilitation treatment integrated with the Tymo system on several patient's features. (2) Methods: We studied a population of 16 patients with Parkinson's Disease. Each recruited subject completed 10 treatment sessions, organized as two training sessions per week, for 5 weeks. The intervention included 30 min of traditional therapy and 20 min of technological treatment with a robotic system. PIADS is composed of three subscales (Competence subscale, Adaptability subscale, Self-esteem subscale) ranging from -3 to +3, reflecting, respectively, a negative or positive feeling towards the device. (3) Results: The Competence subscale, measuring feelings of competence and usefulness, obtained a score of 1.24 (SD = 0.78). The score of Adaptability subscale, indicating a willingness to try out new things and to take risks, was 1.83 (SD = 0.65). Finally, the Self-esteem subscale, indicating feelings of emotional health and happiness, reached a score of 1.31 (SD = 0.72). Moreover, statistical analysis reveals a significant effect on balance performance after intervention. (4) Conclusions: This feasibility study represents a starting point in the use of technology in the rehabilitation pathway of patients affected by Parkinson's Disease. In fact, our results suggest that a standard therapy combined with an innovative treatment using Tymo may be accepted by PD patients, which may benefit especially from preserving balance.

摘要

(1)背景:帕金森病(PD)是导致老年人残疾的最常见原因之一。PD 的晚期阶段通常以姿势不稳为特征,进而导致跌倒。这些是决定 PD 患者生活质量、发病率和死亡率的主要因素之一。在 PD 康复领域,机器人技术也在迅速发展。作为主要目标,我们使用辅助设备心理社会影响量表(PIADS)评估技术集成干预的可接受性,以分析参与者对 Tymo 系统的态度。作为次要结果,我们评估了与 Tymo 系统集成的康复治疗对患者多项特征的治疗效果。(2)方法:我们研究了 16 名 PD 患者的人群。每位入组的患者完成了 10 次治疗,每周组织 2 次训练,共 5 周。干预包括 30 分钟的传统治疗和 20 分钟的机器人系统技术治疗。PIADS 由三个分量表(能力分量表、适应性分量表、自尊分量表)组成,范围从-3 到+3,分别反映对设备的负面或正面感觉。(3)结果:能力分量表,衡量能力感和有用感,得分为 1.24(SD=0.78)。适应性分量表的分数为 1.83(SD=0.65),表明愿意尝试新事物和冒险。最后,自尊分量表,反映情感健康和幸福感,得分为 1.31(SD=0.72)。此外,统计分析显示干预后平衡性能有显著效果。(4)结论:这项可行性研究代表了在 PD 患者康复途径中使用技术的起点。事实上,我们的结果表明,标准治疗与使用 Tymo 的创新治疗相结合可能会被 PD 患者接受,这可能特别有益于平衡的保持。

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Microglial Activation and Inflammation as a Factor in the Pathogenesis of Progressive Supranuclear Palsy (PSP).小胶质细胞激活与炎症作为进行性核上性麻痹(PSP)发病机制中的一个因素
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