Maggiolo F, Sampietro C, Maladorno D, Torre D
Boll Ist Sieroter Milan. 1986;65(2):153-6.
217 children were studied by IFA technique to assess the incidence and prevalence of infections due to L. pneumophila and micdadei. The study was completed by a bacteriological environmental research. No acute infection was detected. Nevertheless 10.1% of all patients showed positive antibody titers. This percentage was 0 in children aged less than 1 year and reached 17.7% in children after 3. Most positive sera were due to a pooled antigen containing L. pneumophila serotypes 1, 2, 3. All environmental samples were negative. Our results demonstrate that our area has probably a low endemicity and that children are a low risk population. Nevertheless the absence of acute pulmonary pathology either during the period of investigation or at the anamnestic report seems to strengthen the reported possibility of infection without major pulmonary signs, with a course as an influenza-like syndrome or as an inapparent infection.
采用间接荧光抗体技术（IFA）对217名儿童进行研究，以评估嗜肺军团菌和麦氏军团菌感染的发病率和患病率。该研究通过细菌学环境研究得以完善。未检测到急性感染。然而，所有患者中有10.1%显示抗体滴度呈阳性。该百分比在1岁以下儿童中为0，在3岁以上儿童中达到17.7%。大多数阳性血清是由于含有嗜肺军团菌血清型1、2、3的混合抗原所致。所有环境样本均为阴性。我们的结果表明，我们所在地区可能地方性流行程度较低，儿童是低风险人群。然而，在调查期间或既往病史报告中均未出现急性肺部病变，这似乎强化了所报道的无明显肺部体征的感染可能性，其病程表现为类似流感综合征或隐性感染。
