Zhao Jiazheng, Zhao Yi, Ma Xiaowei, Feng Helin, Gao Xiaoyan
Department of Orthopedics, The Fourth Hospital of Hebei Medical University Shijiazhuang 050011, Hebei, China.
Department of Neurosurgery, The Fourth Hospital of Hebei Medical University Shijiazhuang 050011, Hebei, China.
Am J Transl Res. 2022 Feb 15;14(2):1123-1130. eCollection 2022.
Breast cancer is the most frequent non-skin cancer in women and bone is its most common site of metastasis. The patella, as the largest sesamoid bone in the human body, is a rare site for cancer metastasis to occur. We reported the comprehensive auxiliary examination data and complete process of diagnosis, management and follow-up for a case of solitary patellar metastasis from breast cancer.
A 47-year-old woman presented with patellar pain 6 years after breast cancer surgery. Thorough imaging and pathology examinations were carried out leading to a diagnosis of breast-derived patellar metastasis. Subsequent treatment and follow-up were performed. The patient recovered function slightly at 3 months postoperatively, but tibia and femur metastases developed at 6 months postoperatively and the patient started radiotherapy.
Cases of patellar metastases from malignant tumors are extremely rare but do exist. Due to the insidious onset and non-specific symptoms, it is worthwhile to alert clinicians. The diagnostic value of positron emission tomography/computed tomography for patellar metastases is significant and still provides certain advantages compared to pathologic examination, so it can be given priority. Prompt postoperative radiotherapy is necessary, while imaging should be actively performed with a short review interval.
乳腺癌是女性中最常见的非皮肤癌,骨骼是其最常见的转移部位。髌骨作为人体最大的籽骨,是癌症转移的罕见部位。我们报告了一例乳腺癌孤立性髌骨转移病例的综合辅助检查数据以及完整的诊断、治疗和随访过程。
一名47岁女性在乳腺癌手术后6年出现髌骨疼痛。进行了全面的影像学和病理学检查,诊断为乳腺来源的髌骨转移。随后进行了治疗和随访。患者术后3个月功能稍有恢复,但术后6个月出现胫骨和股骨转移,患者开始接受放疗。
恶性肿瘤的髌骨转移病例极为罕见,但确实存在。由于起病隐匿且症状不具特异性,值得临床医生警惕。正电子发射断层扫描/计算机断层扫描对髌骨转移的诊断价值显著,与病理检查相比仍具有一定优势,因此可优先考虑。术后及时放疗是必要的,同时应积极进行影像学检查,并缩短复查间隔时间。