Li Gang, Shan Changxing, Sun Ran, Liu Song, Chen Song, Song Mingzhi, Lu Ming
Department of Orthopaedics, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116011, P.R. China.
Department of Orthopaedics, Xiangyang Central Hospital, The Affiliated Hospital of Hubei University of Arts and Science, Xiangyang, Hubei 441021, P.R. China.
Oncol Lett. 2018 Feb;15(2):1389-1396. doi: 10.3892/ol.2017.7478. Epub 2017 Nov 23.
Although bone tumors are frequently located in the knee area, primary tumors of the patella are rare and patellar metastases are even rarer. Knee pain is the most common complaint of patients with patellar metastases. Owing to the low incidence of patellar metastases, misdiagnosis is not unusual. The present review analyzes ~44 cases of patellar metastases originating from distinct primary sites. Reports of malignant tumors of the lung and kidney metastasizing to the patella were more common than those of other patellar metastases. Relative incidence, symptomatology, imaging features, histopathology and treatment options for these patellar metastatic lesions are described respectively along with a review of the literature. Despite numerous experiments demonstrating the reasons for implantation of tumor in patella, the answer to this question has not yet been revealed. In the light of the increasing attention on the diagnosis and the treatment of these lesions, the availability of the integrated information regarding metastases in the patella becomes more relevant.
尽管骨肿瘤常位于膝关节区域,但髌骨原发性肿瘤罕见,而髌骨转移瘤更是少见。膝关节疼痛是髌骨转移瘤患者最常见的主诉。由于髌骨转移瘤发病率低,误诊并不罕见。本综述分析了约44例源自不同原发部位的髌骨转移瘤病例。肺和肾恶性肿瘤转移至髌骨的报道比其他髌骨转移瘤更为常见。分别描述了这些髌骨转移瘤病变的相对发病率、症状、影像学特征、组织病理学及治疗选择,并对文献进行了综述。尽管有大量实验探究肿瘤植入髌骨的原因,但这个问题的答案尚未揭晓。鉴于对这些病变的诊断和治疗越来越受到关注,有关髌骨转移瘤综合信息的可得性就显得更为重要。