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使用烟囱和潜望镜进行腹主动脉瘤和胸腹主动脉瘤的血管内修复与不良结局相关。

Endovascular repair of abdominal and thoracoabdominal aneurysms using chimneys and periscopes is associated with poor outcomes.

机构信息

Division of Vascular Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA.

Division of Vascular Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA.

出版信息

J Vasc Surg. 2022 Aug;76(2):311-317. doi: 10.1016/j.jvs.2022.02.048. Epub 2022 Mar 8.

Abstract

OBJECTIVE

Chimneys and periscopes are often used to treat pararenal or thoracoabdominal aneurysms de novo or after failed open or endovascular repair. We sought to describe our institutional experience, given their limited success and questionable long-term outcomes.

METHODS

We retrospectively reviewed the electronic records for patients treated with chimneys/periscopes from 1997 through 2020. Baseline characteristics, procedural details, periprocedural complications, reinterventions, and midterm outcomes were collected.

RESULTS

Fifty-eight patients (86 vessels) were treated; the median follow-up was 32 months (range, 0.03-104 months). There were 36% (n = 21) juxta-renal, 2% (n = 1) para-visceral, and 21% (n = 12) thoracoabdominal aneurysms, and 41% (n = 24) had pararenal failure of prior endovascular aneurysm repair (n = 17) or open repair (n = 7). Stent configuration for the majority of the 86 vessels (n = 80; 93%) treated were chimney configuration (n = 6 periscopes; 7%). The most common stent graft utilized was Viabahn, and 8.1% (n = 7) were reinforced with a bare metal stent. Although the majority of the cases were elective, 36.2% (n = 21) of the cases were urgent/emergent. At the conclusion of the initial procedure, 16 of 58 patients had an endoleak (gutter, 50% [8/16]; type Ia, 25% [4/16]; and type II, 25% [4/16]). On follow-up, 14 of 58 patients developed one or more endoleaks, with the most common endoleaks being a gutter endoleak (35% [7/20]). Other endoleaks observed included 30% (6/20) type III, 15% (3/20) type Ia, 15% (3/20) type Ib, and 5% (1/20) type II. Eleven of 58 patients underwent interventions for one or more endoleak (gutter, 33% [5/15]; type Ib, 20% [3/15]; type II, 7% [1/15]; and type III, 40% [6/15]). Twelve of 58 patients returned to the operating room for one or more procedures during the index hospitalization (five laparotomies, three dialysis access, three acute limb ischemia, and four chimney/periscope interventions). Ten of 58 patients underwent angioplasty/stenting for chimney/periscope compression or occlusion during the follow-up period. Survival was 61.3% at 1 year by Kaplan-Meier analysis (75% for elective, 37% for urgent/emergent) (aneurysm-related death, 22%). Cox hazard modeling showed that aneurysm diameter (hazard ratio, 1.03; 95% confidence interval, 1.004-1.05; P = .02) and urgent/emergent interventions (hazard ratio, 3.6; 95% confidence interval, 1.33-9.74; P = .01) were predictors of mortality.

CONCLUSIONS

Endovascular repair of aortic aneurysms with chimneys/periscopes is associated with poor outcomes, including limited technical success and aneurysm exclusion, as well as high morbidity and mortality, with a high rate of reinterventions both in the immediate postoperative period and on follow-up. They should be used only when other surgical or endovascular options are not possible.

摘要

目的

烟囱和潜望镜常用于治疗肾周或胸腹主动脉瘤,无论是初次发病还是先前开放或血管内修复失败后。我们旨在描述我们的机构经验,鉴于其有限的成功率和可疑的长期结果。

方法

我们回顾性地审查了 1997 年至 2020 年期间接受烟囱/潜望镜治疗的患者的电子记录。收集了基线特征、手术细节、围手术期并发症、再干预和中期结果。

结果

58 例患者(86 支血管)接受了治疗;中位随访时间为 32 个月(范围,0.03-104 个月)。21%(n=21)为肾下型,2%(n=1)为腹膜后型,21%(n=12)为胸腹主动脉瘤,41%(n=24)为先前血管内动脉瘤修复(n=17)或开放修复(n=7)失败的肾周区。86 支血管(n=80;93%)的支架构型为烟囱构型(n=6 支潜望镜;7%)。最常用的支架移植物是 Viabahn,8.1%(n=7)用裸金属支架加固。虽然大多数病例为择期手术,但 36.2%(n=21)为紧急/急诊手术。在初始手术结束时,58 例患者中有 16 例(16/58)存在内漏(槽型,50%[8/16];Ia 型,25%[4/16];II 型,25%[4/16])。58 例患者中有 14 例在随访期间发生了一个或多个内漏,最常见的内漏是槽型内漏(35%[7/20])。观察到的其他内漏包括 30%(6/20)的 III 型、15%(3/20)的 Ia 型、15%(3/20)的 Ib 型和 5%(1/20)的 II 型。58 例患者中有 11 例因一个或多个内漏(槽型,33%[5/15];Ib 型,20%[3/15];II 型,7%[1/15];和 III 型,40%[6/15])进行了干预。58 例患者中有 12 例在索引住院期间因一个或多个程序返回手术室(5 例剖腹手术、3 例透析通路、3 例急性肢体缺血和 4 例烟囱/潜望镜干预)。58 例患者中有 10 例在随访期间因烟囱/潜望镜压迫或闭塞进行了血管成形术/支架置入术。Kaplan-Meier 分析显示,1 年生存率为 61.3%(择期手术为 75%,紧急/急诊手术为 37%)(动脉瘤相关死亡率,22%)。Cox 风险模型显示,动脉瘤直径(风险比,1.03;95%置信区间,1.004-1.05;P=0.02)和紧急/急诊干预(风险比,3.6;95%置信区间,1.33-9.74;P=0.01)是死亡的预测因素。

结论

使用烟囱/潜望镜进行主动脉瘤的血管内修复与不良结果相关,包括技术成功率和动脉瘤排除率有限,以及高发病率和死亡率,在围手术期和随访期间都有很高的再干预率。只有在其他手术或血管内选择不可行时,才应使用它们。

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