1 Clinic for Cardiovascular Surgery, Institute of Anesthesiology, University Hospital, Zurich, Switzerland.
J Endovasc Ther. 2013 Oct;20(5):597-605. doi: 10.1583/13-4372.1.
To evaluate the performance of periscope and/or chimney grafts (CPGs) in the endovascular treatment of pararenal or thoracoabdominal aneurysms using off-the-shelf devices.
Between February 2002 and August 2012, 77 consecutive patients (62 men; mean age 73±9 years) suffering from pararenal aortic (n=55), thoracoabdominal (n=16), or arch to visceral artery aneurysms (n=6) were treated with aortic stent-graft implantation requiring chimney and/or periscope grafts to maintain side branch perfusion. CPGs were planned in advance and were not used as bailout. A standardized follow-up protocol including computed tomographic angiography, laboratory testing, and clinical examination was performed at 6 weeks; 3, 6, and 12 months; and annually thereafter.
Technical success was achieved in 76 (99%) patients; 1 branch stent-graft became dislocated from a renal artery, which could not be re-accessed. Overall, 169 target vessels (121 renal arteries, 30 superior mesenteric arteries, 17 celiac trunks, and 1 inferior mesenteric artery) were addressed with the chimney graft configuration in 111 and the periscope graft configuration in 58. In total, 228 devices were used for the CPGs: 213 Viabahn stent-grafts and 15 bare metal stents. Over a mean 25±16 months (range 1-121), 9 patients died of unrelated causes. Nearly all (95%) of the patients demonstrated a decreased or stable aneurysm size on imaging; there was a mean 13% shrinkage in aneurysm diameter. Twenty patients had primary type I/III endoleaks at discharge; in follow-up, only 3 of these were still present (no secondary or recurrent endoleaks were noted). Additional endovascular maneuvers were required for CPG-related complications in 13 patients from intervention throughout follow-up. Overall, 4 CPGs occluded (98% target vessel patency); no stent-graft migration was observed. Renal function remained stable in all patients.
In this series, the use of CPGs has proven to be a feasible, safe, and effective way to treat thoracoabdominal and pararenal aneurysms with maintenance of blood flow to the renovisceral arteries. Nearly all of the aneurysms showed no increase in diameter over a >2-year mean follow-up, which supports the midterm adequacy of the CPG technique as a method to effectively revascularize branch vessels with few endoleaks or branch occlusions.
评估使用市售器械行腔内治疗肾周或胸腹主动脉瘤时,使用潜望镜和/或烟囱移植物(CPG)的性能。
2002 年 2 月至 2012 年 8 月,连续 77 例患者(62 例男性;平均年龄 73±9 岁)患有肾周主动脉(n=55)、胸腹主动脉(n=16)或主动脉弓内脏动脉动脉瘤(n=6),需行主动脉支架移植术,以维持侧支灌注。CPG 预先规划,不作为抢救措施。采用包括计算机断层血管造影、实验室检查和临床检查的标准化随访方案,分别在 6 周、3、6 和 12 个月以及此后每年进行一次。
76 例(99%)患者达到技术成功;1 枚分支支架从肾动脉脱位,无法再次进入。共处理了 169 个靶血管(121 个肾动脉、30 个肠系膜上动脉、17 个腹腔干和 1 个肠系膜下动脉),其中 111 例采用烟囱移植物构型,58 例采用潜望镜移植物构型。共使用 228 个 CPG 装置:213 个 Viabahn 支架和 15 个裸金属支架。平均随访 25±16 个月(范围 1-121),9 例患者死于无关原因。几乎所有(95%)患者的瘤体直径在影像学上均有缩小或稳定;瘤体直径平均缩小 13%。20 例患者出院时存在原发性Ⅰ/Ⅲ型内漏;随访时,仅 3 例仍存在(无继发性或复发性内漏)。在整个随访过程中,13 例患者因 CPG 相关并发症需要进一步行血管内干预。总的来说,4 个 CPG 闭塞(98%的靶血管通畅);未观察到支架移植物移位。所有患者的肾功能均保持稳定。
在本系列中,CPG 的使用已被证明是一种可行、安全和有效的方法,可用于治疗胸腹主动脉瘤和肾周动脉瘤,同时保持肾内脏动脉的血流。超过 2 年的平均随访时间内,几乎所有的动脉瘤均未出现直径增大,这支持 CPG 技术作为一种有效再通分支血管的方法,其发生内漏或分支闭塞的风险较低。