Kato Toru, Kimura Yasutoshi, Kubo Tomohiro, Murota Ayako, Hasegawa Tadashi, Takemasa Ichiro
Department of Surgery, Surgical Oncology and Science, Sapporo Medical University School of Medicine, S1 W16, Chuo-ku, Sapporo, Hokkaido 060-8543, Japan.
Department of Medical Oncology and Hematology, Sapporo Medical University School of Medicine, S1 W16, Chuo-ku, Sapporo, Hokkaido 060-8543, Japan.
Int J Surg Case Rep. 2022 Mar;92:106915. doi: 10.1016/j.ijscr.2022.106915. Epub 2022 Mar 4.
Carcinosarcoma of the gallbladder is a rare tumor with both carcinoma and sarcoma components.
In this paper, we report two cases. The first case is of a man in his 60s who was preoperatively diagnosed with gallbladder carcinosarcoma and has achieved 6 years and 6 months survival through aggressive surgical treatment. The second case is of a woman in her 70s who was diagnosed with locally advanced gallbladder cancer; she underwent multidisciplinary treatment for the same, but died 8 months after the surgery. While the primary disorder was the same in both cases, the clinical courses contrasted sharply.
There is no established chemotherapy or radiation therapy for gallbladder carcinosarcoma, and the only curative treatment is surgery. However, it has a very poor prognosis.
Carcinosarcoma of the gallbladder may progress very rapidly, and the treatment management should be carefully decided.
胆囊癌肉瘤是一种罕见的肿瘤，兼具癌和肉瘤成分。
在本文中，我们报告两例病例。第一例是一名60多岁的男性，术前被诊断为胆囊癌肉瘤，通过积极的手术治疗已存活6年6个月。第二例是一名70多岁的女性，被诊断为局部晚期胆囊癌；她接受了多学科治疗，但术后8个月死亡。虽然两例的原发性疾病相同，但临床病程截然不同。
对于胆囊癌肉瘤，尚无既定的化疗或放疗方法，唯一的根治性治疗是手术。然而，其预后非常差。
胆囊癌肉瘤可能进展非常迅速，治疗方案应谨慎决定。
