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一种基于太赫兹反射光谱的液体鉴别新型几何乘积策略。

A novel strategy regarding geometric product for liquids discrimination based on THz reflection spectroscopy.

机构信息

Key Laboratory of Terahertz Optoelectronics, Ministry of Education, Department of Physics, Capital Normal University, Beijing 100048, China; Department of Medical Laboratory, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.

Department of Medical Laboratory, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.

出版信息

Spectrochim Acta A Mol Biomol Spectrosc. 2022 Jun 5;274:121104. doi: 10.1016/j.saa.2022.121104. Epub 2022 Mar 3.

Abstract

A novel expression of geometric product that associated with the geometric relationship from geometric algebra constructed by the vectorized refractive index and absorption coefficient in THz region is proposed, which could provide a new insight into the THz properties of materials. From the novel expression, the candidate characteristic parameters are extracted for liquids discrimination and present the abundant second order correlation information of optical parameters with the consideration of dimension rising. Three groups of liquids, containing C-reactive protein calibrators and alpha fetoprotein calibrators, were selected as examples to validate the feasibility of the proposed strategy. Comparing with the traditional THz parameters, including refractive index, absorption coefficient, and complex permittivity, the novel approach exhibits notable superiority for differentiation with the evaluation of statistical differences and effect sizes. The proposed geometric product expression could have a large potential on promoting the substance identification in some applications of THz technology.

摘要

提出了一种与太赫兹区域中由矢量化折射率和吸收系数构建的几何代数的几何关系相关的新型几何积表达式,这为材料的太赫兹特性提供了新的视角。从新的表达式中,提取出候选特征参数,用于液体鉴别,并呈现出丰富的二阶相关光学参数信息,同时考虑了维度上升。选择三组液体,包括 C 反应蛋白校准品和甲胎蛋白校准品,作为实例验证了所提出策略的可行性。与传统的太赫兹参数(折射率、吸收系数和复介电常数)相比,该新方法在区分方面表现出显著的优势,评估了统计差异和效果大小。所提出的几何积表达式在太赫兹技术的一些应用中对促进物质识别具有很大的潜力。

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