Department of Dietetics, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang 43400, Malaysia.
Department of Dietetics, Hospital Pengajar Universiti Putra Malaysia, Serdang 43400, Malaysia.
Nutrients. 2022 Jan 27;14(3):548. doi: 10.3390/nu14030548.
Background: Weight loss is well-known among head and neck (HNC) patients during radiotherapy and could continue after the treatment is completed. Weight monitoring is essential for treatment outcomes and cancer surveillance. The purpose of the study is to evaluate the weight loss during and post-treatment among HNC patients. Methods: A total of 45 out of 50 patients post-treatment were included in this secondary treatment. Data were collected at baseline, at the completion of radiotherapy and one month after completion of radiotherapy. Results: The mean weight loss was 4.53 ± 2.87 kg (7.4%) during treatment and 1.38 ± 2.65 kg (2.1%) post-treatment. There were significant improvements one month after completion of radiotherapy in Patient-Generated Subjective Global Assessment (PGSGA), muscle mass, nutrition impact symptoms (NIS) score, energy and protein from oral intake (p < 0.0001). Energy and protein from oral nutritional supplements (ONS) decreased significantly (p < 0.0001). Conclusions: The results of this study underline the importance of early identification and monitoring post-treatment in HNC patients. The post-treatment recovery stage is very important for HNC patients to ensure a healing process.
在头颈部（HNC）患者接受放射治疗期间，体重减轻是众所周知的，并且在治疗完成后可能会继续。体重监测对于治疗结果和癌症监测至关重要。本研究的目的是评估 HNC 患者在治疗期间和治疗后的体重减轻情况。
共有 50 名接受治疗后的患者中的 45 名被纳入本项二次治疗研究。数据在基线、放射治疗完成时和放射治疗完成后一个月收集。
治疗期间平均体重减轻 4.53 ± 2.87 公斤（7.4%），治疗后一个月体重减轻 1.38 ± 2.65 公斤（2.1%）。放射治疗完成后一个月，患者主观整体评估（PGSGA）、肌肉量、营养影响症状（NIS）评分、口服摄入的能量和蛋白质均显著改善（p < 0.0001）。口服营养补充剂（ONS）中的能量和蛋白质显著减少（p < 0.0001）。
本研究结果强调了早期识别和监测 HNC 患者治疗后情况的重要性。治疗后恢复期对头颈部癌症患者非常重要，以确保其康复过程。
