Department of Rehabilitation Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Spinal Cord. 2022 May;60(5):375-381. doi: 10.1038/s41393-022-00776-z. Epub 2022 Mar 11.
Meta-analysis.
This study aimed to evaluate the effect of transcutaneous electrical nerve stimulation in people with pain after spinal cord injury by meta-analysis.
Reviewed PubMed, Embase, Cochrane library, as well as China National Knowledge Infrastructure (CNKI), Wanfang, and Vip databases to search the randomized controlled trials of pain after spinal cord injury through transcutaneous electrical nerve stimulation from the beginning of the library to March 2021, and analyze the literature with RevMan 5.3 software and the bias in the literature with STATA 12.0 software.
There are six randomized controlled trials in the study with 165 cases. 83 cases in the test group were given transcutaneous electrical nerve stimulation, and 82 cases in the control group used sham stimulation or other treatments. Meta-analysis results showed the experimental group's visual analog scale (MD = -1.52, 95%CI, -2.44 to -0.60, P = 0.001) and short-form McGill pain questionnaire scores (MD = -0.70, 95% CI, -1.03 to -0.25, P = 0.002) were lower than those of the control group.
Transcutaneous electrical nerve stimulation has some clinical therapeutic effects on persons with pain after spinal cord injury, but due to the lack of literature, the sample size is not large, and clinical trials need to be further improved later.
荟萃分析。
本研究旨在通过荟萃分析评估经皮神经电刺激对脊髓损伤后疼痛人群的疗效。
检索PubMed、Embase、Cochrane 图书馆以及中国知网(CNKI)、万方和维普数据库,检索时间均从建库至 2021 年 3 月,纳入经皮神经电刺激治疗脊髓损伤后疼痛的随机对照试验,采用 RevMan 5.3 软件对文献进行分析,采用 STATA 12.0 软件对文献偏倚进行分析。
本研究纳入 6 项随机对照试验,共 165 例患者。试验组 83 例采用经皮神经电刺激治疗,对照组 82 例采用假刺激或其他治疗。荟萃分析结果显示,试验组视觉模拟评分(MD=-1.52,95%CI:-2.44 至-0.60,P=0.001)和简短 McGill 疼痛问卷评分(MD=-0.70,95%CI:-1.03 至-0.25,P=0.002)均低于对照组。
经皮神经电刺激对脊髓损伤后疼痛患者具有一定的临床治疗效果,但由于文献缺乏、样本量不大,后期还需要进一步开展临床试验加以改进。