Halliday Lucy, Nelson Scott M, Kearns Rachel J
School of Medicine, University of Glasgow, Glasgow, UK.
Int J Gynaecol Obstet. 2022 Nov;159(2):356-364. doi: 10.1002/ijgo.14175. Epub 2022 Mar 21.
Lumbar epidural is the most effective form of pain relief in labor with around 30% of laboring women in the UK and 60% in the USA receiving epidural analgesia. Associations of epidural on maternal, obstetric, and neonatal outcomes have been the subject of intense study, though a number of uncertainties persist. The present narrative review explores important areas of research surrounding epidural analgesia in obstetric patients including methods of initiation and administration, choice of local anesthetic solution, and the addition of adjuvants. Key meta-analyses exploring associations of epidural analgesia on maternal and neonatal outcomes are identified and summarized.
腰椎硬膜外麻醉是分娩时最有效的镇痛方式，在英国约30%的产妇以及美国60%的产妇接受硬膜外镇痛。硬膜外麻醉对母体、产科及新生儿结局的影响一直是深入研究的主题，尽管仍存在一些不确定性。本叙述性综述探讨了产科患者硬膜外镇痛相关的重要研究领域，包括启动和给药方法、局部麻醉溶液的选择以及辅助药物的添加。识别并总结了探索硬膜外镇痛与母体和新生儿结局之间关系的关键荟萃分析。
