Coviello Antonio, Iacovazzo Carmine, Frigo Maria Grazia, Ianniello Marilena, Cirillo Dario, Tierno Giuseppe, de Siena Andrea Uriel, Buonanno Pasquale, Servillo Giuseppe
Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples "Federico II", via Sergio Pansini 5, Naples, 80100, Italy.
UOSD, Obstetric Anesthesia and Resuscitation, Isola Tiberina Hospital - Gemelli Isola, Rome, 00186, Italy.
J Anesth Analg Crit Care. 2025 Jan 29;5(1):6. doi: 10.1186/s44158-025-00224-3.
Labor analgesia is increasingly widespread throughout the world with a rate ranging from 10 to 60%. The benefits regarding clinical and non-clinical maternal-fetal outcomes are currently discussed in international scientific literature. Even stage of labor needs a different and appropriate approach to control the pain; however, different techniques are reported in literature. The following study intends to give a brief overview of the characteristics of the different neuraxial and non-neuraxial techniques currently available and the non-technical skills necessary for effective assistance to pregnant women, providing insights on the topic to understand critical issues at the same time. After bibliographic research since 2018 to 2023, many randomized controlled trials, literature reviews, systematic reviews, and metanalysis were evaluated to create this brief overview. The following pharmacological and non-pharmacological approaches were assessed: spinal techniques, such as epidural analgesia (EA), combined spinal-epidural (CSE), dural puncture epidural (DPE), and continuous spinal anesthesia (CSA); pharmacological administration of nitrous oxide (NO) and systemic opioids (morphine, fentanyl, and pethidine); as the third one transcutaneous electric nerve stimulation (TENS), acupressure/acupuncture, aromatherapy, and breathing exercises. All the assessed approaches are relatively safe and effective, but the association of technical and non-technical skills is needed to improve the maternal and fetus outcome. More studies are needed to clarify what is the best approach to labor analgesia.
分娩镇痛在全球范围内越来越普遍,使用率在10%至60%之间。目前,国际科学文献正在讨论其对临床和非临床母婴结局的益处。即使在分娩的不同阶段,也需要不同且合适的方法来控制疼痛;然而,文献中报道了不同的技术。以下研究旨在简要概述目前可用的不同神经轴和非神经轴技术的特点,以及有效帮助孕妇所需的非技术技能,同时提供对该主题的见解,以了解关键问题。在对2018年至2023年的文献进行研究后,评估了许多随机对照试验、文献综述、系统评价和荟萃分析,以创建此简要概述。评估了以下药理学和非药理学方法:脊髓技术,如硬膜外镇痛(EA)、腰麻-硬膜外联合阻滞(CSE)、硬膜穿刺硬膜外阻滞(DPE)和连续脊髓麻醉(CSA);一氧化二氮(NO)和全身性阿片类药物(吗啡、芬太尼和哌替啶)的药物给药;作为第三种方法的经皮电神经刺激(TENS)、指压/针灸、芳香疗法和呼吸练习。所有评估的方法相对安全有效,但需要技术和非技术技能的结合来改善母婴结局。需要更多的研究来阐明分娩镇痛的最佳方法是什么。