Im Hyunjae, Choe Hyun Woo, Oh Seung-Young, Ryu Ho Geol, Lee Hannah
Department of Critical Care Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
Acute Crit Care. 2022 May;37(2):237-246. doi: 10.4266/acc.2021.01095. Epub 2022 Feb 24.
The Life-Sustaining Treatment (LST) Decisions Act allows withholding and withdrawal of LST, including cardiopulmonary resuscitation (CPR). In the present study, the incidence of CPR before and after implementation of the Act was compared.
This was a retrospective review involving hospitalized patients who underwent CPR at a single center between February 2016 and January 2020 (pre-implementation period, February 2016 to January 2018; post-implementation period, February 2018 to January 2020). The primary outcome was monthly incidence of CPR per 1,000 admissions. The secondary outcomes were duration of CPR, return of spontaneous circulation (ROSC) rate, 24-hour survival rate, and survival-to-discharge rate. The study outcomes were compared before and after implementation of the Act.
A total of 867 patients who underwent CPR was included in the analysis. The incidence of CPR per 1,000 admissions showed no significant difference before and after implementation of the Act (3.02±0.68 vs. 2.81±0.75, P=0.255). The ROSC rate (67.20±0.11 vs. 70.99±0.12, P=0.008) and survival to discharge rate (20.24±0.09 vs. 22.40±0.12, P=0.029) were higher after implementation of the Act than before implementation.
The incidence of CPR did not significantly change for 2 years after implementation of the Act. Further studies are needed to assess the changes in trends in the decisions of CPR and other LSTs in real-world practice.
维持生命治疗(LST)决策法案允许 withhold 和撤销维持生命治疗,包括心肺复苏(CPR)。在本研究中,比较了该法案实施前后心肺复苏的发生率。
这是一项回顾性研究,纳入了 2016 年 2 月至 2020 年 1 月在单一中心接受心肺复苏的住院患者(实施前阶段,2016 年 2 月至 2018 年 1 月;实施后阶段,2018 年 2 月至 2020 年 1 月)。主要结局是每 1000 例入院患者的每月心肺复苏发生率。次要结局是心肺复苏持续时间、自主循环恢复(ROSC)率、24 小时生存率和出院生存率。比较了该法案实施前后的研究结局。
共有 867 例接受心肺复苏的患者纳入分析。每 1000 例入院患者的心肺复苏发生率在该法案实施前后无显著差异(3.02±0.68 对 2.81±0.75,P = 0.255)。该法案实施后的 ROSC 率(67.20±0.11 对 70.99±0.12,P = 0.008)和出院生存率(20.24±0.09 对 22.40±0.12,P = 0.029)高于实施前。
该法案实施后 2 年,心肺复苏发生率无显著变化。需要进一步研究以评估实际临床实践中心肺复苏和其他维持生命治疗决策趋势的变化。