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根据RECOVER指南对犬猫进行心肺复苏的前瞻性评估。第2部分:指南实施后的患者预后及心肺复苏实践

Prospective Evaluation of Cardiopulmonary Resuscitation Performed in Dogs and Cats According to the RECOVER Guidelines. Part 2: Patient Outcomes and CPR Practice Since Guideline Implementation.

作者信息

Hoehne Sabrina N, Hopper Kate, Epstein Steven E

机构信息

William R. Pritchard Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis, Davis, CA, United States.

Department of Veterinary Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis, Davis, CA, United States.

出版信息

Front Vet Sci. 2019 Dec 10;6:439. doi: 10.3389/fvets.2019.00439. eCollection 2019.

Abstract

Cardiopulmonary resuscitation (CPR) outcomes have not been prospectively described since implementation of the Reassessment Campaign on Veterinary Resuscitation (RECOVER) guidelines. This study aimed to prospectively describe CPR outcomes and document arrest variables in dogs and cats at a U.S. veterinary teaching hospital since implementation of the RECOVER guidelines using the 2016 veterinary Utstein-style CPR reporting guidelines. One-hundred and seventy-two dogs and 47 cats that experienced cardiopulmonary arrest (CPA) underwent CPR following implementation of the RECOVER guidelines and were prospectively included. Supervising clinicians completed a data form for CPR events immediately following completion of CPR from December 2013 to June 2018. Seventy-five (44%) dogs and 26 (55%) cats attained return of spontaneous circulation (ROSC), 45 dogs (26%) and 16 cats (34%) had ROSC ≥ 20 min, 13 dogs (8%) and 10 cats (21%) were alive 24 h after CPR, and 12 dogs (7%) and 9 cats (19%) survived to hospital discharge. The most common cause of death in animals with ROSC ≥ 20 min was euthanasia. Patient outcomes were not significantly different since publication of the RECOVER guidelines except for a higher feline survival to hospital discharge rate. Dogs ( = 0.02) but not cats with initial shockable rhythms had increased rates of ROSC while the development of a shockable rhythm during CPR efforts was not associated with ROSC ( = 0.30). In closed chest CPR an end-tidal carbon dioxide (EtCO) value of >16.5 mmHg was associated with a 75% sensitivity and 64% specificity for achieving ROSC. Since publication of the RECOVER guidelines, CPR practice did not clinically significantly change at our institution and no improvement of already high ROSC rates was noted. The percentage of cats surviving to hospital discharge was higher than previously reported and the reason for this improvement is not evident with these results. Euthanasia remains a major confounding factor in assessing intermediate and long-term CPR outcomes in dogs and cats.

摘要

自实施《兽医复苏再评估运动(RECOVER)指南》以来,尚未对心肺复苏(CPR)的结果进行前瞻性描述。本研究旨在自实施RECOVER指南以来,在美国一家兽医教学医院,使用2016年兽医Utstein式CPR报告指南,前瞻性描述CPR结果并记录犬猫的心跳骤停变量。172只犬和47只猫经历了心肺骤停(CPA),在实施RECOVER指南后接受了CPR,并被前瞻性纳入研究。监督临床医生在2013年12月至2018年6月完成CPR后,立即填写CPR事件的数据表。75只(44%)犬和26只(55%)猫实现了自主循环恢复(ROSC),45只犬(26%)和16只猫(34%)的ROSC≥20分钟,13只犬(8%)和10只猫(21%)在CPR后24小时存活,12只犬(7%)和9只猫(19%)存活至出院。ROSC≥20分钟的动物中最常见的死亡原因是安乐死。自RECOVER指南发布以来,除了猫存活至出院的比例较高外,患者的预后没有显著差异。初始可电击心律的犬(P = 0.02)而非猫的ROSC发生率增加,而CPR过程中出现可电击心律与ROSC无关(P = 0.30)。在闭胸CPR中,呼气末二氧化碳(EtCO)值>16.5 mmHg与实现ROSC的敏感性为75%、特异性为64%相关。自RECOVER指南发布以来,我们机构CPR的临床实践没有显著变化,也未发现已较高的ROSC发生率有所改善。存活至出院的猫的比例高于先前报道,而这些结果并未明确这种改善的原因。安乐死仍然是评估犬猫CPR中期和长期结果的主要混杂因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f4d/6914737/edc1ffe7091d/fvets-06-00439-g0001.jpg

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