Devins G M, Binik Y M, Mandin H, Burgess E D, Taub K, Letourneau P K, Buckle S, Low G L
Int J Psychiatry Med. 1986;16(2):151-62. doi: 10.2190/rryp-70xh-77ce-ddgx.
End-stage renal disease (ESRD) is recognized as imposing severe psychosocial stresses upon patients with the result that depression is believed to be highly prevalent. A number of studies have reported low levels of depression, however, and this contradictory finding has been explained via the construct of defensive denial-i.e., patients may minimize the impact of illness-related experiences upon their overall experiences of life. The present study tested this hypothesis in a sample of seventy ESRD patients. Participants rated a series of twelve life dimensions (e.g., work, family and martial relations, recreation) in terms of perceived intrusiveness and control as well as indicating their perceived similarity using a card sort task. Standard measures of depression, positive and negative moods, somatic symptoms of distress, self-esteem, and life happiness were also obtained via structured interviews. A multidimensional scaling analysis applied to the card sort data indicated that ESRD patients do, indeed, perceive illness-related and nonillness aspects of life as independent. However, an analysis of partial variance-controlling for age and nonrenal health-failed to provide evidence of defensive denial. The suggestion is forwarded that previous findings of a high prevalence of depression in ESRD may be in error due to the misidentification of uremic symptoms as symptoms of depression.
终末期肾病(ESRD)被认为会给患者带来严重的心理社会压力,导致抑郁症被认为极为普遍。然而,一些研究报告称抑郁症水平较低,这一矛盾的发现已通过防御性否认的概念来解释,即患者可能会尽量减少与疾病相关的经历对其整体生活体验的影响。本研究在70名ESRD患者的样本中检验了这一假设。参与者根据感知到的侵扰性和控制程度对一系列12个生活维度(如工作、家庭和婚姻关系、娱乐)进行评分,并通过卡片分类任务表明他们感知到的相似性。还通过结构化访谈获得了抑郁症、积极和消极情绪、痛苦的躯体症状、自尊和生活幸福感的标准测量值。对卡片分类数据进行的多维尺度分析表明,ESRD患者确实将生活中与疾病相关和与疾病无关的方面视为相互独立的。然而,在控制年龄和非肾脏健康因素的偏方差分析中,未能提供防御性否认的证据。有人提出,先前关于ESRD中抑郁症高患病率的研究结果可能有误,原因是将尿毒症症状误识别为抑郁症症状。