老年缺血性脑卒中患者多种药物联用安全性的循证总结
Evidence-based summary for the safety of multiple medication in elderly patients with ischemic stroke.
作者信息
Tian Xingyue, Yu Manchi, Sun Yifei, Yan Hongyun, Ma Huiqing, Jiang Ling, Zhu Yueqin, Wang Linfeng, Ding Qi, Liu Aixia
机构信息
Department of Neurology, Suzhou Municipal Hospital, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, China.
Department of Internal Medicine, Suzhou Municipal Hospital, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, China.
出版信息
Ann Transl Med. 2022 Feb;10(4):202. doi: 10.21037/atm-22-453.
BACKGROUND
To retrieve, analyze, and summarize the relevant evidence of home-based medications use for stroke patients, so as to provide evidence for safe home-based medication of elderly patients with ischemic stroke.
METHODS
We performed a search in the databases of () Best Practice, UpToDate, Joanna Briggs Institute (JBI) Evidence-based Health Care Center Library, Cochrane Library, PubMed, China National Knowledge Infrastructure (CNKI), Wanfang Knowledge Data Service Platform, and others, according to the evidence pyramid model. We retrieved all evidence on the safety of home-based multiple medications use in elderly patients with ischemic stroke, including clinical decision-making, expert consensus, guidelines, systematic reviews, and summary of evidence. The search time limit was from the establishment of the database to March 2021. The literature evaluation standard and evidence grading system of JBI Evidence-based Health Care Center were used to evaluate the quality of the literature, and to classify the extracted evidence.
RESULTS
A total of 17 articles were included in this study, comprising 2 guidelines, 11 systematic reviews, 3 evidence summaries, and 1 expert consensus. This article summarizes the 7 best evidences from 5 aspects: drug dispensing, drug identification, medication time, prescription simplification, and self-management plan.
CONCLUSIONS
The evidence of home-based multiple medication use in elderly patients with ischemic stroke provides an evidence-based reference for ensuring the safety of medications for patients, and guides elderly patients with ischemic stroke and their caregivers by applying the best available evidence.
背景
检索、分析和总结脑卒中患者居家用药的相关证据，为老年缺血性脑卒中患者居家安全用药提供依据。
方法
按照证据金字塔模型，在（）最佳实践、UpToDate、乔安娜·布里格斯循证卫生保健中心图书馆、考克兰图书馆、PubMed、中国知网、万方知识数据服务平台等数据库进行检索。检索老年缺血性脑卒中患者居家联合用药安全性的所有证据，包括临床决策、专家共识、指南、系统评价和证据总结。检索时限为各数据库建库至2021年3月。采用乔安娜·布里格斯循证卫生保健中心的文献评价标准和证据分级系统对文献质量进行评价，并对提取的证据进行分类。
结果
本研究共纳入17篇文献，其中包括2篇指南、11篇系统评价、3篇证据总结和1篇专家共识。本文从药物调配、药物识别、用药时间、简化处方和自我管理计划5个方面总结了7条最佳证据。
结论
老年缺血性脑卒中患者居家联合用药的证据为确保患者用药安全提供了循证参考，并通过应用最佳可得证据指导老年缺血性脑卒中患者及其照护者。
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