一例抗SAE1皮肌炎病例。
A Case of Anti-SAE1 Dermatomyositis.
作者信息
de Vries Max, Schreurs Marco W J, Ahsmann Els J M, Spee-Dropkova Marcela, Karim Faiz
机构信息
Department of Internal Medicine, Groene Hart Hospital, Bleulandweg 10 2803 HH, Gouda, Netherlands.
Department of Immunology, Erasmus MC, University Medical Center, Postbus 2040 3000 CA, Rotterdam, Netherlands.
出版信息
Case Reports Immunol. 2022 Mar 4;2022:9000608. doi: 10.1155/2022/9000608. eCollection 2022.
INTRODUCTION
Anti-SAE1 antibodies have a low prevalence in dermatomyositis patients. . A 61-year-old woman presented with progressive shortness of breath, arthralgia, heliotrope rash, Gottron's papules, and erythematous rash. She had an interstitial lung disease (ILD) with a significant decrease in lung function. There was no muscle involvement. Immunological laboratory test results showed strongly positive anti-SAE1 antibodies. Glucocorticoid treatment resulted in remission of dermatomyositis.
CONCLUSION
Anti-SAE antibodies in dermatomyositis patients are closely linked to unique clinical features.
引言
抗SAE1抗体在皮肌炎患者中的患病率较低。一名61岁女性出现进行性气短、关节痛、向阳疹、Gottron丘疹和红斑疹。她患有间质性肺病（ILD），肺功能显著下降。无肌肉受累。免疫实验室检查结果显示抗SAE1抗体强阳性。糖皮质激素治疗使皮肌炎缓解。
结论
皮肌炎患者中的抗SAE抗体与独特的临床特征密切相关。
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