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角化型多形性腺瘤:一种罕见的位于不寻常部位的变体。

Keratinizing pleomorphic adenoma: A rare variant in an unusual location.

作者信息

Sankari S Leena, Dhanavelu Prakash, Priya P Sangeetha, Jimson Sudha

机构信息

Department of Oral Pathology and Microbiology, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, Chennai, Tamil Nadu, India.

Department of Oral and Maxillofacial Surgery, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, Chennai, Tamil Nadu, India.

出版信息

J Oral Maxillofac Pathol. 2021 Sep-Dec;25(3):557. doi: 10.4103/jomfp.jomfp_362_21. Epub 2022 Jan 11.

DOI:10.4103/jomfp.jomfp_362_21
PMID:35281182
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8859603/
Abstract

Pleomorphic adenoma is the most common benign salivary gland tumour characterized by great histologic diversity. The presence of extensive squamous metaplasia and numerous keratin pearls is mostly uncommon in the microscopic study and can signify a potential pitfall in the histopathological diagnosis Pleomorphic adenoma can show the presence of squamous metaplasia with keratin pearls as a rare finding and is encountered most often in the parotid gland (84%) and 6% in the minor salivary gland. Here we present a case report of a rare histopathological variant of pleomorphic adenoma with exuberant squamous metaplasia and keratin pearl formation of the minor salivary gland in an unusual location.

摘要

多形性腺瘤是最常见的涎腺良性肿瘤,其组织学表现具有高度多样性。在显微镜检查中,广泛的鳞状化生和大量角质珠的出现大多并不常见,这可能意味着组织病理学诊断中存在潜在的陷阱。多形性腺瘤可表现为鳞状化生伴角质珠形成,这是一种罕见的表现,最常发生于腮腺(84%),小涎腺中占6%。在此,我们报告一例罕见的多形性腺瘤组织病理学变异病例,该病例发生于小涎腺的一个不寻常部位,伴有旺盛的鳞状化生和角质珠形成。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3831/8859603/a1c04eff4320/JOMFP-25-557b-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3831/8859603/651198e61a35/JOMFP-25-557b-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3831/8859603/24968b137965/JOMFP-25-557b-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3831/8859603/d97c7c757302/JOMFP-25-557b-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3831/8859603/a1c04eff4320/JOMFP-25-557b-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3831/8859603/651198e61a35/JOMFP-25-557b-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3831/8859603/24968b137965/JOMFP-25-557b-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3831/8859603/d97c7c757302/JOMFP-25-557b-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3831/8859603/a1c04eff4320/JOMFP-25-557b-g004.jpg

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引用本文的文献

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本文引用的文献

1
Pleomorphic adenomas of the salivary glands: retrospective multicentric study of 130 cases with emphasis on histopathological features.涎腺多形性腺瘤:130例回顾性多中心研究,重点关注组织病理学特征
Eur Arch Otorhinolaryngol. 2017 Jan;274(1):543-551. doi: 10.1007/s00405-016-4253-5. Epub 2016 Aug 12.
2
A benign salivary gland tumor of minor salivary gland mimicking an epithelial malignancy.一种酷似上皮性恶性肿瘤的小唾液腺良性涎腺肿瘤。
Contemp Clin Dent. 2015 Apr-Jun;6(2):247-9. doi: 10.4103/0976-237X.156058.
3
Pleomorphic adenoma of the buccal salivary gland.
颊部涎腺多形性腺瘤
J Oral Maxillofac Pathol. 2015 Jan-Apr;19(1):111. doi: 10.4103/0973-029X.157222.
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Pleomorphic adenoma of the palate.腭部多形性腺瘤
Natl J Maxillofac Surg. 2011 Jul;2(2):169-71. doi: 10.4103/0975-5950.94473.
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Anticancer Res. 2005 May-Jun;25(3A):1703-5.