Klein Claudia B
Epigenetics, YENO Evolution GmbH, Vienna, AUT.
Cureus. 2022 Mar 8;14(3):e22962. doi: 10.7759/cureus.22962. eCollection 2022 Mar.
In this pilot study, we report the use of a novel, patented biophysical technology, which enables intranuclear access and cell nucleus stimulation, via the signal of the biophysically activated regulative molecule 31 (RM31). RM31 is the name of an isolated natural molecule found in the human body and is involved in many cellular mechanisms. We used a specific low electromagnetic field frequency to activate the RM31 molecule, which leads to specific signal transduction, to investigate the effect of telomerase activity in HL60 cancer cells. Our results revealed a dramatic inhibition in telomerase activity, a 99.5% decrease within 72 hours, with avoidance of subsequent reactivation, due to the simultaneous inhibition of human telomerase reverse transcriptase (hTERT).
在这项初步研究中，我们报告了一种新型专利生物物理技术的应用，该技术可通过生物物理激活调节分子31（RM31）的信号实现核内进入和细胞核刺激。RM31是在人体中发现的一种分离的天然分子的名称，它参与许多细胞机制。我们使用特定的低电磁场频率激活RM31分子，从而导致特定的信号转导，以研究HL60癌细胞中端粒酶活性的影响。我们的结果显示端粒酶活性受到显著抑制，在72小时内降低了99.5%，并且由于同时抑制了人类端粒酶逆转录酶（hTERT），避免了随后的重新激活。
