慢性中心性浆液性脉络膜视网膜病变与亚临床库欣综合征的关联。
Association of chronic central serous chorioretinopathy with subclinical Cushing's syndrome.
作者信息
Soares Rebecca Russ, Samuelson Annika, Chiang Allen
机构信息
Retina Service, Wills Eye Hospital, Philadelphia, PA, USA.
Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.
出版信息
Am J Ophthalmol Case Rep. 2022 Mar 4;26:101455. doi: 10.1016/j.ajoc.2022.101455. eCollection 2022 Jun.
PURPOSE
To report the clinical course of a patient with central serous chorioretinopathy (CSCR) secondary to subclinical hypercortisolism before and after adrenalectomy.
OBSERVATIONS
A 50-year-old female patient with multifocal, chronic CSCR was found to have an adrenal incidentaloma and was diagnosed with subclinical hypercortisolism. Patient elected to undergo minimally-invasive adrenalectomy and presented at 3 months after surgery without subretinal fluid.
CONCLUSIONS AND IMPORTANCE
Subclinical Cushing's Syndrome (SCS) may present an underrecognized risk factor for developing chronic CSCR. Further investigation is needed to determine the threshold of visual comorbidity that may influence surgical management.
目的
报告1例亚临床皮质醇增多症继发中心性浆液性脉络膜视网膜病变（CSCR）患者肾上腺切除术前、后的临床病程。
观察结果
一名患有多灶性慢性CSCR的50岁女性患者被发现有肾上腺偶发瘤，并被诊断为亚临床皮质醇增多症。患者选择接受微创肾上腺切除术，术后3个月就诊时视网膜下液已消失。
结论与意义
亚临床库欣综合征（SCS）可能是发生慢性CSCR的一个未被充分认识的危险因素。需要进一步研究以确定可能影响手术治疗的视觉合并症阈值。
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