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幸存者的失眠和疲惫:乳腺癌幸存者的疲劳和失眠。

Sleepless and Spent in Survivorship: Fatigue and Insomnia in Breast Cancer Survivors.

机构信息

Hoffman Breast Center, Department of Surgery, RinggoldID:14319Mount Auburn Hospital, Cambridge, MA, USA.

RinggoldID:200750The Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.

出版信息

Am Surg. 2022 Nov;88(11):2730-2736. doi: 10.1177/00031348221078949. Epub 2022 Mar 13.

Abstract

BACKGROUND

It is estimated that there are 3.8 million breast cancer survivors in the United States. Addressing survivors' post-treatment needs is critical to providing quality healthcare.

METHODS

A standardized questionnaire for breast cancer survivors was employed to assess the health status, challenges, and concerns of our breast cancer patients at their survivorship visits, which were conducted 4 months after surgery. All patients were seen in the breast center at one community hospital over a 6-year period.

RESULTS

Responses to a standardized questionnaire that was administered to 505 consecutive breast cancer patients at their survivorship visits 4 months after surgery were evaluated. The most striking finding was that 35% reported symptoms of insomnia, 26% had persistent fatigue, and 19% experienced fatigue that interfered with their usual activities. There was a significant association between symptoms of insomnia and radiation treatment ( = .004), pain ( < .001), hormone therapy ( < .01), and side effects of hormone therapy ( < .0001). There was also a significant association between fatigue and pain ( < .001) as well as side effects from hormone treatment ( = .0036).

CONCLUSIONS

Over a third (35%) of breast cancer patients suffer from insomnia, while over a quarter (26%) complain of fatigue at their survivorship assessments. Contributing factors include radiation treatment, pain, and hormonal therapy. Careful assessment and treatment of fatigue and symptoms of insomnia in breast cancer patients is needed to improve quality of life for survivors.

摘要

背景

据估计,美国有 380 万乳腺癌幸存者。满足幸存者的治疗后需求对于提供高质量的医疗保健至关重要。

方法

采用标准化的乳腺癌幸存者问卷,评估我们的乳腺癌患者在手术后 4 个月的生存随访时的健康状况、挑战和关注点。所有患者在 6 年内都在一家社区医院的乳腺中心就诊。

结果

对 505 例连续乳腺癌患者在手术后 4 个月的生存随访时进行的标准化问卷进行了评估。最引人注目的发现是,35%的患者报告有失眠症状,26%的患者持续疲劳,19%的患者疲劳感影响了他们的日常活动。失眠症状与放疗( =.004)、疼痛( <.001)、激素治疗( <.01)和激素治疗的副作用( <.0001)之间存在显著相关性。疲劳与疼痛( <.001)以及激素治疗的副作用( =.0036)之间也存在显著相关性。

结论

超过三分之一(35%)的乳腺癌患者在生存评估时患有失眠,超过四分之一(26%)的患者抱怨疲劳。促成因素包括放疗、疼痛和激素治疗。需要仔细评估和治疗乳腺癌患者的疲劳和失眠症状,以提高幸存者的生活质量。

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