Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, NC.
Division of Vascular and Endovascular Surgery, Department of Surgery, Duke University Medical Center, Durham, NC.
J Thorac Cardiovasc Surg. 2023 Oct;166(4):996-1008.e1. doi: 10.1016/j.jtcvs.2022.02.016. Epub 2022 Feb 16.
After limited root/ascending with or without hemiarch repair for acute type A aortic dissection (ATAAD), 20% to 30% of patients require distal reintervention, frequently for arch pathology. In this report, we describe an institutional algorithm for arch management after previous limited ATAAD repair and detail operative and long-term outcomes.
From August 2005 to April 2021, 71 patients status post previous limited ATAAD repair underwent reoperative arch repair involving zones 1 to 3 for aneurysmal degeneration of residual arch dissection including complete cervical debranching with zone 0/1 thoracic endovascular aortic repair in 6 (8%), open total arch in 13 (18%), type I hybrid arch repair in 23 (32%), and type II/III hybrid arch repair in 29 (41%).
Mean age was 59 ± 12 years; time from index ATAAD repair to reoperation was 4 (interquartile range, 2-9) years. There were 2 (2.8%) in-hospital deaths and 2 (2.8%) postdischarge deaths within 30 days of surgery. Three patients suffered stroke (4.2%) and 2 (2.8%) had acute renal failure requiring dialysis. Overall Kaplan-Meier survival was 78%, 70%, and 58% at 1, 3, and 5 years, respectively. Institutional experience appeared to play a significant role in early and late outcomes, because there have been no operative mortalities in the past 9 years and improved survival of 87% versus 66%, 79% versus 58%, and 79% versus 40% at 1, 3, and 5 years in comparisons of the past 9 years with the previous era (P = .01).
Aneurysmal degeneration of residual arch dissection after limited ATAAD repair presents a complex reoperative challenge. An algorithmic operative approach tailored to patient anatomy and comorbidities yields excellent early and late outcomes, which continue to improve with increasing institutional experience.
急性 A 型主动脉夹层(ATAAD)行局限性根部/升主动脉修复加或不加半弓修复后,20%至 30%的患者需要再次进行远端干预,通常是由于弓部病变。本报告介绍了一种既往局限性 ATAAD 修复后弓部处理的机构算法,并详细介绍了手术和长期结果。
2005 年 8 月至 2021 年 4 月,71 例既往行局限性 ATAAD 修复的患者因残余弓部夹层动脉瘤样变需再次行弓部修复,包括完全颈侧支血管离断加零区/一区胸主动脉腔内修复术 6 例(8%)、开放全弓置换术 13 例(18%)、I 型杂交弓修复术 23 例(32%)和 II/III 型杂交弓修复术 29 例(41%)。
平均年龄为 59±12 岁;从初次 ATAAD 修复到再次手术的时间为 4(四分位间距,2-9)年。住院期间死亡 2 例(2.8%),术后 30 天内死亡 2 例(2.8%)。3 例发生卒中(4.2%),2 例(2.8%)发生急性肾衰竭需透析。总体 Kaplan-Meier 生存率分别为 1、3 和 5 年的 78%、70%和 58%。机构经验似乎对早期和晚期结果有显著影响,因为在过去的 9 年中没有手术死亡,并且在过去 9 年与前一时期相比,早期和晚期的生存率分别提高了 87%比 66%、79%比 58%和 79%比 40%(P=0.01)。
局限性 ATAAD 修复后残余弓部夹层的动脉瘤样变是一个复杂的再次手术挑战。根据患者的解剖结构和合并症制定算法手术方法,可获得极好的早期和晚期结果,并且随着机构经验的增加,结果还会不断改善。