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急性 A 型主动脉夹层修复术后主动脉弓重建的个体化方法和结果。

Tailored approach and outcomes of aortic arch reconstruction after acute type A dissection repair.

机构信息

Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, NC.

Division of Vascular and Endovascular Surgery, Department of Surgery, Duke University Medical Center, Durham, NC.

出版信息

J Thorac Cardiovasc Surg. 2023 Oct;166(4):996-1008.e1. doi: 10.1016/j.jtcvs.2022.02.016. Epub 2022 Feb 16.

Abstract

OBJECTIVE

After limited root/ascending with or without hemiarch repair for acute type A aortic dissection (ATAAD), 20% to 30% of patients require distal reintervention, frequently for arch pathology. In this report, we describe an institutional algorithm for arch management after previous limited ATAAD repair and detail operative and long-term outcomes.

METHODS

From August 2005 to April 2021, 71 patients status post previous limited ATAAD repair underwent reoperative arch repair involving zones 1 to 3 for aneurysmal degeneration of residual arch dissection including complete cervical debranching with zone 0/1 thoracic endovascular aortic repair in 6 (8%), open total arch in 13 (18%), type I hybrid arch repair in 23 (32%), and type II/III hybrid arch repair in 29 (41%).

RESULTS

Mean age was 59 ± 12 years; time from index ATAAD repair to reoperation was 4 (interquartile range, 2-9) years. There were 2 (2.8%) in-hospital deaths and 2 (2.8%) postdischarge deaths within 30 days of surgery. Three patients suffered stroke (4.2%) and 2 (2.8%) had acute renal failure requiring dialysis. Overall Kaplan-Meier survival was 78%, 70%, and 58% at 1, 3, and 5 years, respectively. Institutional experience appeared to play a significant role in early and late outcomes, because there have been no operative mortalities in the past 9 years and improved survival of 87% versus 66%, 79% versus 58%, and 79% versus 40% at 1, 3, and 5 years in comparisons of the past 9 years with the previous era (P = .01).

CONCLUSIONS

Aneurysmal degeneration of residual arch dissection after limited ATAAD repair presents a complex reoperative challenge. An algorithmic operative approach tailored to patient anatomy and comorbidities yields excellent early and late outcomes, which continue to improve with increasing institutional experience.

摘要

目的

急性 A 型主动脉夹层(ATAAD)行局限性根部/升主动脉修复加或不加半弓修复后,20%至 30%的患者需要再次进行远端干预,通常是由于弓部病变。本报告介绍了一种既往局限性 ATAAD 修复后弓部处理的机构算法,并详细介绍了手术和长期结果。

方法

2005 年 8 月至 2021 年 4 月,71 例既往行局限性 ATAAD 修复的患者因残余弓部夹层动脉瘤样变需再次行弓部修复,包括完全颈侧支血管离断加零区/一区胸主动脉腔内修复术 6 例(8%)、开放全弓置换术 13 例(18%)、I 型杂交弓修复术 23 例(32%)和 II/III 型杂交弓修复术 29 例(41%)。

结果

平均年龄为 59±12 岁;从初次 ATAAD 修复到再次手术的时间为 4(四分位间距,2-9)年。住院期间死亡 2 例(2.8%),术后 30 天内死亡 2 例(2.8%)。3 例发生卒中(4.2%),2 例(2.8%)发生急性肾衰竭需透析。总体 Kaplan-Meier 生存率分别为 1、3 和 5 年的 78%、70%和 58%。机构经验似乎对早期和晚期结果有显著影响,因为在过去的 9 年中没有手术死亡,并且在过去 9 年与前一时期相比,早期和晚期的生存率分别提高了 87%比 66%、79%比 58%和 79%比 40%(P=0.01)。

结论

局限性 ATAAD 修复后残余弓部夹层的动脉瘤样变是一个复杂的再次手术挑战。根据患者的解剖结构和合并症制定算法手术方法,可获得极好的早期和晚期结果,并且随着机构经验的增加,结果还会不断改善。

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