Suppr超能文献

蚌式胸廓胸骨切开术用于选择性主动脉弓病变的一期修复。

Clamshell thoracosternotomy for single-stage repair of select aortic arch pathologies.

作者信息

Prabhu Neel K, Vekstein Andrew M, Jensen Christopher W, Williams Adam R, Gaca Jeffrey G, Hughes G Chad

机构信息

Division of Thoracic and Cardiovascular Surgery, Department of Surgery, Duke University Medical Center, Durham, NC.

出版信息

JTCVS Open. 2024 Nov 16;23:44-50. doi: 10.1016/j.xjon.2024.10.032. eCollection 2025 Feb.

Abstract

OBJECTIVE

Although median sternotomy is widely used for aortic arch repair, the distal extent of arch replacement is limited with this approach. Bilateral thoracosternotomy (clamshell) represents an alternate and underappreciated strategy that allows for single-stage repair of the aortic arch and descending thoracic aorta. We report our institutional experience with this approach.

METHODS

Patients who underwent clamshell thoracosternotomy for aortic arch surgery from 2005 to 2022 were identified from a prospectively maintained institutional aortic surgery database. The primary outcomes were 30-day/in-hospital mortality and major morbidity, including stroke, paraplegia, and renal failure requiring hemodialysis. Secondary outcomes included late overall survival, aorta-specific survival, and freedom from aortic reintervention.

RESULTS

Clamshell thoracosternotomy was performed in 18 patients (67% men) with median age 52 years; 50% (n = 9) had heritable thoracic aortic disease. Clamshell repair indications included focal arch dissection (44%; n = 8), extensive arch aneurysm or pseudoaneurysm (33%; n = 6), complex pediatric coarctation (17%; n = 3), and adult coarctation with ascending aneurysm (6%; n = 1). Operative mortality occurred in 1 patient (6%). No patients developed stroke, paraplegia, or renal failure. Overall actuarial survival was 94% at 1 year and 72% at 5 years, whereas aorta-specific survival was 94% at 1 and 5 years. There were no reinterventions on the contiguous aorta at a median follow-up of 60 months (range, 18-85 months).

CONCLUSIONS

Clamshell thoracosternotomy is a safe approach for single-stage complex open arch with or without descending repair, especially for those with heritable thoracic aortic disease or anatomy not amenable to endovascular therapies.

摘要

目的

尽管正中胸骨切开术广泛用于主动脉弓修复,但采用这种方法时,主动脉弓置换的远端范围有限。双侧胸胸骨切开术(蛤壳式)是一种替代且未得到充分重视的策略,可对主动脉弓和胸降主动脉进行一期修复。我们报告了我们机构采用这种方法的经验。

方法

从一个前瞻性维护的机构主动脉手术数据库中识别出2005年至2022年期间接受蛤壳式胸胸骨切开术进行主动脉弓手术的患者。主要结局为30天/住院死亡率和主要并发症,包括中风、截瘫和需要血液透析的肾衰竭。次要结局包括晚期总生存率、主动脉特异性生存率以及无需主动脉再次干预。

结果

18例患者(67%为男性)接受了蛤壳式胸胸骨切开术,中位年龄52岁;50%(n = 9)患有遗传性胸主动脉疾病。蛤壳式修复的适应证包括局灶性主动脉弓夹层(44%;n = 8)、广泛性主动脉弓瘤或假性动脉瘤(33%;n = 6)、复杂小儿主动脉缩窄(17%;n = 3)以及合并升主动脉瘤的成人主动脉缩窄(6%;n = 1)。1例患者(6%)发生手术死亡。无患者发生中风、截瘫或肾衰竭。1年时的总体精算生存率为94%,5年时为72%,而主动脉特异性生存率在1年和5年时均为94%。在中位随访60个月(范围18 - 85个月)时,连续主动脉未进行再次干预。

结论

蛤壳式胸胸骨切开术是一种安全的方法,可用于有或无降主动脉修复的一期复杂开放性主动脉弓手术,特别是对于那些患有遗传性胸主动脉疾病或解剖结构不适合血管内治疗的患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe50/11883712/a24e23a7299f/ga1.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验