Department of Pulmonary Medicine, Sultan Abdulhamid Han Teaching Hospital, Istanbul, Turkey.
Department of Intensive Care Unit, Sultan Abdulhamid Han Teaching Hospital, Istanbul, Turkey.
J Cardiothorac Vasc Anesth. 2022 Aug;36(8 Pt B):2948-2953. doi: 10.1053/j.jvca.2022.02.009. Epub 2022 Feb 11.
The authors aimed to evaluate the characteristics and management outcomes of patients who developed tracheal stenosis after invasive mechanical ventilation (IMV) due to COVID-19.
DESIGN, SETTING, AND PARTICIPANTS: The data of 7 patients with tracheal stenosis and 201 patients without tracheal stenosis after IMV due to COVID-19 between March 2020 and October 2021 were retrospectively analyzed.
Flexible bronchoscopy was performed for the diagnosis of tracheal stenosis and the evaluation of the treatment's effectiveness, and rigid bronchoscopy was applied for the dilatation of tracheal stenosis.
In the follow-up period, tracheal stenosis was observed in 7 of 208 patients (2 women, 5 men; 3.3%). The patients were divided into 2 groups as patients with tracheal stenosis (n = 7) and patients without tracheal stenosis (n = 201). There were no statistically significant differences between the 2 groups in terms of age, sex, body mass index, and comorbidities (p > 0.05). The mean duration of IMV of the patients with tracheal stenosis was longer than patients without tracheal stenosis (27.9 ± 13 v 11.2 ± 9 days, p < 0.0001, respectively). Three (43%) of the stenoses were web-like and 4 (57%) of them were complex-type stenosis. The mean length of the stenoses was 1.81 ± 0.82 cm. Three of the patients were treated successfully with bronchoscopic dilatation, and 4 of them were treated with tracheal resection.
Tracheal stenosis developed in 7 of 208 (3.3%) patients with COVID-19 who were treated with IMV. The most important characteristic of patients with tracheal stenosis was prolonged IMV support.
评估因 COVID-19 行有创机械通气（IMV）后发生气管狭窄患者的特征和治疗结果。
设计、地点和患者：回顾性分析 2020 年 3 月至 2021 年 10 月间因 COVID-19 行 IMV 后发生气管狭窄的 7 例患者和 201 例无气管狭窄患者的数据。
采用纤维支气管镜诊断气管狭窄并评估治疗效果，采用硬支气管镜扩张气管狭窄。
208 例患者中有 7 例（2 例女性，5 例男性；3.3%）发生气管狭窄。患者分为气管狭窄组（n=7）和无气管狭窄组（n=201）。2 组患者在年龄、性别、体重指数和合并症方面无统计学差异（p＞0.05）。气管狭窄组患者的 IMV 时间长于无气管狭窄组（27.9±13 天比 11.2±9 天，p＜0.0001）。3 例（43%）狭窄呈网状，4 例（57%）为复杂型狭窄。狭窄的平均长度为 1.81±0.82cm。3 例患者经支气管镜扩张治疗成功，4 例患者行气管切除术。
208 例因 COVID-19 行 IMV 的患者中有 7 例（3.3%）发生气管狭窄。气管狭窄患者的重要特征是 IMV 支持时间延长。
