Singh N B, Srivastava K, Gupta H P, Srivastava A, Mathur I S
Indian J Lepr. 1986 Jan-Mar;58(1):38-42.
Lymphnode enlargement produced by strains of mycobacteria have a direct bearing on the immunogenicity characteristics. Two strains of mycobacteria namely M. habana TMC 5135 and M. marinum (SATO) have been studied for their property to produce enlargement of draining lymphnodes besides other cell-mediated immune responses. Both the strains are capable of producing the enlargements of inguinal and popliteal lymphnodes which is very significant. The enlargements of lymphnodes have been produced by these strains both in the live as well as killed state. Possibility of developing these strains as vaccine against leprosy has been discussed.
分枝杆菌菌株引起的淋巴结肿大与免疫原性特征直接相关。已对两株分枝杆菌，即哈瓦那分枝杆菌TMC 5135和海分枝杆菌（佐藤株）进行了研究，除了其他细胞介导的免疫反应外，还研究了它们引起引流淋巴结肿大的特性。这两株菌株都能够引起腹股沟和腘窝淋巴结肿大，这一点非常显著。这些菌株在活态和灭活状态下均可引起淋巴结肿大。文中还讨论了将这些菌株开发成抗麻风病疫苗的可能性。
