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印度东北部甲癣的皮肤镜特征及其与甲板氢氧化钾涂片(KOH)、培养及过碘酸希夫染色(PAS)的相关性

Dermatoscopic Features of Onychomycosis and its Correlation with Nail Plate Potassium Hydroxide Mount (KOH), Culture, and Periodic Acid Schiff Stain (PAS) in North East India.

作者信息

Marak Anita, Verma Shikha, Lyngdoh Wihiwot Valerie, Dey Biswajit

机构信息

Department of Dermatology and STD, North Eastern Indira Gandhi Regional Institute Of Health and Medical Sciences, Mawdiangdiang, Shillong, Meghalaya, India.

Department of Microbiology, North Eastern Indira Gandhi Regional Institute Of Health and Medical Sciences, Mawdiangdiang, Shillong, Meghalaya, India.

出版信息

Indian J Dermatol. 2021 Nov-Dec;66(6):625-631. doi: 10.4103/ijd.ijd_261_21.

Abstract

CONTEXT

Dermatoscopy has been used recently for identifying the specific features of onychomycosis. Very few studies have used it as a diagnostic tool. Our study highlights the specific patterns in different clinical types of onychomycosis and the novel features that have never been reported previously.

AIMS

To study the dermatoscopic patterns in patients with onychomycosis and determine the sensitivity, specificity, positive, and negative predictive values of the different features.

STUDY DESIGN

A cross-sectional study.

MATERIALS AND METHOD

Dermatoscopic picture using dinolite video dermatoscope was taken in patients diagnosed with onychomycosis either with a positive KOH, culture, and/or PAS.

RESULT

A total of 80 patients were included. Onychomycosis was identified in 68 individuals. Clinically, 73.52% presented with distal lateral subungual onychomycosis (DLSO) and 26.47% had total dystrophic (TD). PAS was positive in 85.29% of patients, KOH in 75%, and culture in 66.17%. species were isolated in 53.33%, whereas species in 40% of patients. Dermatoscopic features were seen in all 68 patients (100%). The most common finding in decreasing order includes spike pattern, ruin appearance, distal irregular terminations (DIT), longitudinal striations, chromonychia, focal homogeneous opacities, microsplitting, and uniform homogeneous pattern. Three novel patterns were observed: homogeneous opacity with a-z pattern border, microsplitting in a Christmas tree pattern, and focal homogeneous opacities.

CONCLUSION

To our knowledge, this is the first study conducted in northeast India where dermatoscopy was used as a diagnostic tool and it was found to have the highest sensitivity. New features that have not been described before have been identified.

摘要

背景

皮肤镜检查最近已被用于识别甲真菌病的特定特征。很少有研究将其用作诊断工具。我们的研究突出了不同临床类型甲真菌病的特定模式以及以前从未报道过的新特征。

目的

研究甲真菌病患者的皮肤镜模式,并确定不同特征的敏感性、特异性、阳性和阴性预测值。

研究设计

一项横断面研究。

材料与方法

使用迪诺莱特视频皮肤镜为诊断为甲真菌病且KOH、培养和/或PAS呈阳性的患者拍摄皮肤镜图片。

结果

共纳入80例患者。68例确诊为甲真菌病。临床上,73.52%表现为远端侧位甲下甲真菌病(DLSO),26.47%为全甲营养不良型(TD)。85.29%的患者PAS呈阳性,75%的患者KOH呈阳性,66.17%的患者培养呈阳性。53.33%的患者分离出 种,而40%的患者分离出 种。所有68例患者(100%)均观察到皮肤镜特征。按降序排列最常见的表现包括刺状模式、废墟外观、远端不规则末端(DIT)、纵向条纹、甲变色、局灶性均匀混浊、微裂和均匀一致模式。观察到三种新的模式:带a-z模式边界的均匀混浊、圣诞树模式的微裂和局灶性均匀混浊。

结论

据我们所知,这是印度东北部进行的第一项将皮肤镜用作诊断工具的研究,发现其具有最高的敏感性。已识别出以前未描述过的新特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1db5/8906330/71f629c0b3ba/IJD-66-625-g001.jpg

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