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皮肤镜检查作为甲真菌病诊断的第一步。

Dermoscopy as a first step in the diagnosis of onychomycosis.

作者信息

Yorulmaz Ahu, Yalcin Basak

机构信息

Department of Dermatology, Ankara Numune Research and Education Hospital, Ankara, Turkey.

出版信息

Postepy Dermatol Alergol. 2018 Jun;35(3):251-258. doi: 10.5114/ada.2018.76220. Epub 2018 Jun 18.

Abstract

INTRODUCTION

Over the years, clinical studies have provided new knowledge about the dermoscopic features of the diseases of cutaneous annexes. It seems that dermoscopy has opened a new morphological dimension in the diagnosis and management of hair disorders and onychopathies.

AIM

To identify and describe dermoscopic features of onychomycosis.

MATERIAL AND METHODS

A total of 81 consecutive patients with onychomycosis (55 men and 26 women) were prospectively enrolled in the present study. For each patient, all fingernails and toenails were evaluated in clinical and dermoscopic examinations. Mycological tests were performed by potassium hydroxide (KOH) preparation. Mann-Whitney and χ tests were used for the statistical analysis, with a significance threshold of < 0.05.

RESULTS

Dermoscopic examination of the patients' nails revealed the following: jagged proximal edge with spikes of the onycholytic area (51.9%), longitudinal streaks and patches (44.4%), subungual hyperkeratosis (27.2%), brown-black pigmentation (9.9%) and leukonychia (1.2%). Jagged proximal edge, subungual hyperkeratosis and leukonychia were positively associated with the onychomycosis type.

CONCLUSIONS

Onychomycosis accounts for up to 50% of all consultations for onychopathies. Fast and effective diagnostic approaches are needed in everyday clinical practice. Dermoscopy can provide immediate and accurate information in the diagnosis of onychomycosis. We suggest that dermoscopy should be taken as a first step toward the diagnosis of onychomycosis.

摘要

引言

多年来,临床研究提供了有关皮肤附属器疾病皮肤镜特征的新知识。皮肤镜似乎在毛发疾病和甲病的诊断与管理方面开启了一个新的形态学维度。

目的

识别并描述甲癣的皮肤镜特征。

材料与方法

本研究前瞻性纳入了连续81例甲癣患者(55例男性和26例女性)。对每位患者的所有手指甲和脚趾甲进行临床和皮肤镜检查。通过氢氧化钾(KOH)制剂进行真菌学检测。采用Mann-Whitney检验和χ检验进行统计分析,显著性阈值为<0.05。

结果

对患者指甲的皮肤镜检查发现如下情况:甲分离区近端边缘呈锯齿状且有尖刺(51.9%)、纵向条纹和斑片(44.4%)、甲下过度角化(27.2%)、棕黑色色素沉着(9.9%)和白甲(1.2%)。锯齿状近端边缘、甲下过度角化和白甲与甲癣类型呈正相关。

结论

甲癣占所有甲病会诊病例的比例高达50%。日常临床实践中需要快速有效的诊断方法。皮肤镜可在甲癣诊断中提供即时准确的信息。我们建议皮肤镜检查应作为甲癣诊断的第一步。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9d2/6041705/0383664e4ac3/PDIA-35-32956-g001.jpg

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