Reddy Sainath, Manchanda Isheeta, Godse Kiran, Patil Anant D
Department of Dermatology, Dr. DY Patil Medical College, Nerul, Navi Mumbai, Maharashtra, India.
Department of Pharmacology, Dr. DY Patil Medical College, Nerul, Navi Mumbai, Maharashtra, India.
Indian J Dermatol. 2021 Nov-Dec;66(6):705. doi: 10.4103/ijd.ijd_446_21.
Chronic urticaria is a heterogenous skin disorder representing one of the important reasons for consultation with a dermatologist. Dermatology post-graduate students play an importanrt role in the treatment of patients with chronic urticaria.
The objective of the study was to describe clinical characteristics of patients with chronic urticaria and assess adherence to the guidelines by postgraduate students in the department of dermatology of a tertiary care center.
In this retrospective study, prescriptions of patients with chronic urticaria and/or angioedema presenting to the outpatient department for 5 months were analyzed. Percentage of prescriptions adhering to international urticaria management guidelines was calculated. Urticaria Activity Score, percentage of patients receiving second-generation antihistamines, first-generation antihistamines, and other drugs was recorded. Comorbidities in patients with chronic urticaria were also noted.
A total of 60 patients (mean age 32.1 years; 58.3% male) were included in. Mean (SD) duration of urticaria at the time of study was 4.7 (2.7) months. Demographism and history of allergy to drugs was present in 45 (75%) and 4 (6.7%) patients. Mean (SD) Urticaria Activity Score was 12.5 (6.5). A total of 12 (20%) patients had comorbidities. Mean number of drugs received per patient was 1.7 (0.5). A total of 47 (78.3%) patients received second-generation antihistamines, whereas 11 (18.3%) received first-generation antihistamines. Two (3.3%) patients received combination of first-generation and second-generation antihistamines. Fexofenadine, levocetirizine, bilastine, and cetirizine was prescribed to 24 (40%), 26 (43.3%), 18 (30%), and 14 (23.3%) patients. There was no significant difference in male and female patients receiving fexofenadine ( = 0.59) or levocetirizine ( = 0.13).
Adherence to urticaria management guidelines by resident doctors in dermatology department in our institute was satisfactory.
慢性荨麻疹是一种异质性皮肤疾病,是皮肤科医生会诊的重要原因之一。皮肤科研究生在慢性荨麻疹患者的治疗中发挥着重要作用。
本研究的目的是描述慢性荨麻疹患者的临床特征,并评估三级医疗中心皮肤科研究生对指南的遵循情况。
在这项回顾性研究中,分析了5个月内到门诊就诊的慢性荨麻疹和/或血管性水肿患者的处方。计算符合国际荨麻疹管理指南的处方百分比。记录荨麻疹活动评分、接受第二代抗组胺药、第一代抗组胺药和其他药物治疗的患者百分比。还记录了慢性荨麻疹患者的合并症。
共纳入60例患者(平均年龄32.1岁;58.3%为男性)。研究时荨麻疹的平均(标准差)病程为4.7(2.7)个月。45例(75%)患者有过敏体质,4例(6.7%)患者有药物过敏史。平均(标准差)荨麻疹活动评分为12.5(6.5)。共有12例(20%)患者有合并症。每位患者接受的药物平均数量为1.7(0.5)。共有47例(78.3%)患者接受第二代抗组胺药治疗,而11例(18.3%)患者接受第一代抗组胺药治疗。2例(3.3%)患者接受第一代和第二代抗组胺药联合治疗。分别有24例(40%)、26例(43.3%)、18例(30%)和14例(23.3%)患者使用非索非那定、左西替利嗪、比拉斯汀和西替利嗪。接受非索非那定(P = 0.59)或左西替利嗪(P = 0.13)治疗的男性和女性患者之间无显著差异。
我院皮肤科住院医生对荨麻疹管理指南的遵循情况令人满意。