国家早期预警评分（NEWS）2可预测新冠肺炎患者的医院死亡率。
National early warning score (NEWS) 2 predicts hospital mortality from COVID-19 patients.
作者信息
Wibisono Eric, Hadi Usman, Arfijanto Muhammad Vitanata, Rusli Musofa, Rahman Brian Eka, Asmarawati Tri Pudy, Choirunnisa Miftahani Leo, Rahayu Dwi Retno Puji
机构信息
Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.
Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga - Airlangga University Teaching Hospital, Surabaya, Indonesia.
出版信息
Ann Med Surg (Lond). 2022 Apr;76:103462. doi: 10.1016/j.amsu.2022.103462. Epub 2022 Mar 8.
BACKGROUND
COVID-19 has a high risk of mortality, especially in patients with comorbid diseases such as cardiac disease, type 2 diabetes mellitus, chronic kidney disease, and hypertension. The National Early Warning Score (NEWS) is a tool that helps in identifying changes in patient conditions that require intensive treatment.
OBJECTIVE
Analyzing NEWS-2 to identify the risk of death in COVID-19 patients.
METHODS
This research was conducted from June to July 2020 by using quota sampling. The number of participants in this study was 112 participants (case group = 56 participants and control group = 56 participants). Participants were assessed for NEWS-2 and evaluated for their treatment outcomes. The analysis used in this study was the Chi-squared test and logistic regression with p < 0.05.
RESULTS
45 participants died of having NEWS-2 score >5, and as many as 50 participants showed an improvement in their condition by having NEWS-2 score 5 (OR = 34.091; < 0.001). The accuracy of NEWS-2's assessment of mortality of COVID-19 patients had a sensitivity of 80.4% and a specificity of 89.3%. There were several comorbid diseases that had a significant relationship on mortality of COVID-19 patients such as cardiac disease ( = 5.907; 1.107-31.527 95% CI; = 0.038), T2DM ( = 3.143; 1.269-7.783 95% CI; = 0.013), CKD ( = 3.851; 1.195-12.416 95% CI; = 0.024), and hypertension ( = 2.820; 1.075-7.399 95% CI; = 0.035).
CONCLUSION
The NEWS-2 can be used to identify the risk of death of COVID-19 patients.
背景
新型冠状病毒肺炎（COVID-19）具有较高的死亡风险，尤其是在患有心脏病、2型糖尿病、慢性肾脏病和高血压等合并症的患者中。国家早期预警评分（NEWS）是一种有助于识别需要强化治疗的患者病情变化的工具。
目的
分析NEWS-2以确定COVID-19患者的死亡风险。
方法
本研究于2020年6月至7月采用配额抽样法进行。本研究的参与者有112名（病例组=56名参与者，对照组=56名参与者）。对参与者进行NEWS-2评估，并对其治疗结果进行评估。本研究采用的分析方法是卡方检验和p<0.05的逻辑回归。
结果
45名NEWS-2评分>5的参与者死亡，50名NEWS-2评分为5的参与者病情有所改善（比值比=34.091；<0.001）。NEWS-2对COVID-19患者死亡率评估的准确性具有80.4%的敏感性和89.3%的特异性。有几种合并症与COVID-19患者的死亡率有显著关系，如心脏病（比值比=5.907；95%置信区间为1.107-31.527；p=0.038）、2型糖尿病（比值比=3.143；9s%置信区间为1.269-7.783；p=0.013）、慢性肾脏病（比值比=3.851；95%置信区间为1.195-12.416；p=0.024）和高血压（比值比=2.820；95%置信区间为1.075-7.399；p=0.035）。
结论
NEWS-2可用于识别COVID-19患者的死亡风险。
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